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{"Asthenia": 2.0297665972138086, "Cardiac failure": 2.1326734237511453, "Death": 6.644593702886772, "Disease progression": 2.428502090800721, "Dysphagia": 5.337199756249735, "General physical health deterioration": 2.256908028393501, "Hospitalisation": 3.607536407949742, "Hyperkeratosis": 31.339646439611634, "Hyperpyrexia": 16.748828454881412, "Malignant melanoma": 26.51803200313268, "Malignant neoplasm progression": 10.074603566996371, "Metastases to central nervous system": 35.97684734159338, "Metastases to lung": 10.738587887181808, "Metastatic malignant melanoma": 127.91629892137396, "Neutropenia": 2.0196736576082213, "Palmoplantar keratoderma": 337.1039155598279, "Product use in unapproved indication": 2.324539554268213, "Pyrexia": 3.2416631478560416, "Skin papilloma": 56.4605016308825, "Uveitis": 33.144610733618265}