{"acquired gene mutation": 343.86, "acute kidney injury": 4.18, "diarrhoea": 2.58, "disease progression": 13.53, "drug interaction": 4.94, "drug resistance": 107.08, "hepatitis": 15.83, "hepatotoxicity": 32.39, "malignant neoplasm progression": 14.19, "neoplasm progression": 10.18, "neutropenia": 2.3, "palmar-plantar erythrodysaesthesia syndrome": 10.58, "pancreatitis": 5.8, "product use in unapproved indication": 8.58, "pulmonary embolism": 4.65}