diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/902.json new file mode 100644 index 00000000000..c8279d64e9d --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/902.json @@ -0,0 +1 @@ +{"Acute myeloid leukaemia ": 133.503888480076, "Disease progression ": 6.680034192039005, "Myelodysplastic syndrome ": 76.19645250821675} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/903.json new file mode 100644 index 00000000000..e817070fef4 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/903.json @@ -0,0 +1 @@ +{"Drug interaction ": 9.530118811960705, "Immune reconstitution inflammatory syndrome ": 165.08883489826445, "Psychiatric decompensation ": 663.2396778811935} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/904.json new file mode 100644 index 00000000000..628e72b84d2 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/904.json @@ -0,0 +1 @@ +{"Amnesia ": 3.06078726370813, "Angina pectoris ": 8.825517861269901, "Balance disorder ": 2.683423784712419, "Blood creatinine increased ": 2.1424472983394653, "Blood pressure decreased ": 2.9908112504184854, "Bradycardia ": 3.3454798236021865, "Cardiac failure ": 2.222919889838336, "Chromaturia ": 14.44729951282272, "Confusional state ": 2.508211412146361, "Constipation ": 8.068916833641287, "Disorientation ": 2.815224351009764, "Dizziness ": 4.163421604969596, "Drug interaction ": 3.80848408579945, "Dry mouth ": 5.052210979262974, "Dyspepsia ": 2.473764833965856, "Dysuria ": 2.742075923854959, "Electrocardiogram QT prolonged ": 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b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/905.json new file mode 100644 index 00000000000..1a5a8ee1d2c --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/905.json @@ -0,0 +1 @@ +{"Cough ": 16.44471447742089, "Dyspnoea ": 7.711475812665724, "Lower respiratory tract infection ": 119.9638786744081} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/906.json new file mode 100644 index 00000000000..ec78425e817 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/906.json @@ -0,0 +1 @@ +{"Angina pectoris ": 18.4296308397781, "Blood creatinine increased ": 2.227887020088801, "Cardiac arrest ": 3.9003529525993774, "Cardiac disorder ": 3.482669517586212, "Cardiac failure congestive ": 3.6445841185602887, "Cardiac operation ": 38.77372094667076, "Cardiac 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"Blood cholesterol increased ": 2.743195193501178, "Blood creatinine increased ": 4.45681864788023, "Blood triglycerides increased ": 4.762726277158749, "Body height decreased ": 6.121524703993062, "Cardiac disorder ": 2.206845174363937, "Cellulitis ": 2.474994073095889, "Cerebrovascular accident ": 2.4515180498800824, "Clostridium difficile infection ": 2.521642374968734, "Cytomegalovirus infection ": 6.987375344366411, "Deep vein thrombosis ": 2.814376747756138, "Dementia ": 2.856320574446203, "Diabetes mellitus ": 4.2154013296973, "Drug effective for unapproved indication ": 12.753466944716411, "Drug ineffective for unapproved indication ": 7.076652082996148, "Drug interaction ": 2.0279716493801816, "Drug level below therapeutic ": 15.167214969841057, "Drug level decreased ": 15.113397122277602, "Drug level increased ": 13.023604657935833, "End stage renal disease ": 2.7184021550693958, "Expired product administered ": 5.443644555469545, "Fluid retention ": 2.5186913686275254, "Graft versus host disease ": 14.836480259728772, "Haemolytic uraemic syndrome ": 82.5573018803982, "Heart transplant ": 109.08693549545588, "Heart transplant rejection ": 73.29288153381675, "Hernia ": 15.53870714872362, "Hip fracture ": 4.306724710695486, "Hyperlipidaemia ": 4.326524495775605, "Hypertriglyceridaemia ": 8.74494750542327, "Illness ": 3.262851459588308, "Immune system disorder ": 4.540348188406744, "Immunosuppressant drug level increased ": 77.82861309558291, "Impaired healing ": 7.3023644694553855, "Infection ": 3.43904112994251, "Interstitial lung disease ": 6.669387723052361, "Kidney transplant rejection ": 70.55575082485579, "Liver transplant ": 18.514104413007264, "Liver transplant rejection ": 63.632980704996754, "Localised infection ": 3.538862940170233, "Lower limb fracture ": 3.0883412065560827, "Lung disorder ": 4.837676975714129, "Lung infiltration ": 11.919951611047733, "Lung neoplasm malignant ": 3.047617199088322, "Lymphoedema ": 15.377927480648806, 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b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/909.json new file mode 100644 index 00000000000..6472ba56f26 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/909.json @@ -0,0 +1 @@ +{"Angina pectoris ": 9.12085758322994, "Atrioventricular block ": 57.79364215928979, "Atrioventricular block complete ": 50.46396821372571, "Blood pressure decreased ": 14.938304259971554, "Bradycardia ": 14.424446752245444, "Bronchospasm ": 24.44311556697105, "Cardiac arrest ": 27.998892804404505, "Chest discomfort ": 8.074860891370413, "Chest pain ": 2.6491982543369024, "Discomfort ": 19.64906753404985, "Dizziness ": 3.008945610127116, "Dyspnoea ": 4.027842570568169, "Heart rate decreased ": 22.20754325626869, "Heart rate increased ": 4.62292254968632, "Hypotension ": 8.68470687019341, "Incorrect product administration duration ": 28.680268685146057, "Loss of consciousness ": 2.5571452123022893, "Nausea ": 2.129869984020443, "Presyncope ": 4.7424936056094, "Sinus bradycardia ": 29.78775491236836, "Vomiting ": 2.4269932621366284} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/91.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/91.json new file mode 100644 index 00000000000..c27d700a71d --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/91.json @@ -0,0 +1 @@ +{"Asthma ": 5.792623423146339, "Blood pressure increased ": 5.199049149517635, "Chest discomfort ": 5.198410548048072, "Drug hypersensitivity ": 8.843767800274412, "Drug interaction ": 7.476289550973353, "Erectile dysfunction ": 30.072979219334247, "Hypertension ": 4.718602907149649, "Palpitations ": 3.6073794538208888, "Rash ": 2.092873464103183, "Throat tightness ": 36.33814622424957, "Urticaria ": 3.0349387013136786, "Wheezing ": 11.781719784092292} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/910.json new file mode 100644 index 00000000000..e4c42bf6cb2 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/910.json @@ -0,0 +1 @@ +{"Completed suicide ": 11.766182062559732, "Drug interaction ": 5.698655364636911, "Erectile dysfunction ": 41.3728581767196, "Impulse-control disorder ": 882.9245621992858, "Product use in unapproved indication ": 8.103199376948977, "Suicidal ideation ": 14.328539877611613, "Therapeutic product ineffective ": 305.2553639664196} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/911.json new file mode 100644 index 00000000000..3381eb1f16b --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/911.json @@ -0,0 +1 @@ +{"Blood bilirubin increased ": 11.154015452356177, "Blood lactate dehydrogenase increased ": 23.64673172684285, "Blood phosphorus increased ": 146.31354052446963, "Cardio-respiratory arrest ": 9.647796496922636, "Cardiovascular insufficiency ": 168.13610249659004, "Cerebral haematoma ": 73.30766422279504, "Cerebrovascular accident ": 3.08446484991966, "Chromaturia ": 25.7463132108657, "General physical health deterioration ": 8.370152932510361, "Haemolysis ": 138.26491241134434, "Haemolytic anaemia ": 154.15323944948963, "Haptoglobin decreased ": 437.31840994707375, "Hyperkalaemia ": 13.236460270616377, "Hypoxia ": 45.70352594967808, "Incorrect dose administered ": 8.514772546174397, "Methaemoglobinaemia ": 3269.9253194698936, "Nervous system disorder ": 19.946357158042847, "Oxygen saturation decreased ": 15.4096195532012, "Renal failure ": 2.247069171503802, "Respiratory failure ": 10.899152514129948, "Tumour lysis syndrome ": 142.40462717353353, "Ventricular fibrillation ": 29.93153726263183} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/912.json new file mode 100644 index 00000000000..cd62f5b838c --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/912.json @@ -0,0 +1 @@ +{"Acute kidney injury ": 3.020724710497884, "Angina pectoris ": 2.3125374202489866, "Angioedema ": 7.8232050529932655, "Anuria ": 3.9037176749672513, "Arrhythmia ": 2.036727684458403, "Atrioventricular block ": 3.3427948123194016, "Blood creatine increased ": 7.777418992279464, "Blood creatine phosphokinase increased ": 2.1304693899691984, "Blood creatinine increased ": 11.644014727329289, "Blood potassium decreased ": 2.0338621189914603, "Blood potassium increased ": 21.579952684977307, "Blood pressure abnormal ": 3.2204012504825035, "Blood pressure decreased ": 4.021953918358298, "Blood pressure diastolic decreased ": 18.59601325356756, "Blood pressure diastolic increased ": 13.765266594494973, "Blood pressure fluctuation ": 14.248234425507968, "Blood pressure inadequately controlled ": 110.24126918567978, "Blood pressure increased ": 12.384733768824791, "Blood pressure systolic decreased ": 6.780974278636445, "Blood pressure systolic increased ": 24.80130467433001, "Blood urea increased ": 18.10853668605657, "Blood uric acid increased ": 7.805911395008172, "Bradycardia ": 2.4043878779475967, "Brain natriuretic peptide increased ": 10.385910757321168, "Bundle branch block left ": 8.672868725766053, "Cerebrovascular accident ": 3.022984048799418, "Circulatory collapse ": 2.292286114997746, "Creatinine renal clearance decreased ": 12.017358610443214, "Dermatitis bullous ": 2.6820779592674424, "Diabetes mellitus ": 3.525906977290141, "Dysphagia ": 2.4838974968758816, "Extrasystoles ": 6.111300369107672, "Eyelid oedema ": 2.5551337913991423, "Face oedema ": 6.311605107907201, "Fluid retention ": 2.982521017744182, "Gamma-glutamyltransferase increased ": 3.882335517987928, "Generalised oedema ": 5.463655145441369, "Glomerular filtration rate decreased ": 14.738760835681012, "Glycosylated haemoglobin increased ": 4.017675890279441, "Gynaecomastia ": 3.058078914914629, "Heart rate decreased ": 2.701663508521147, "Hyperkalaemia ": 17.155751588825034, "Hypertension ": 3.4771411470739224, "Hypertensive crisis ": 10.961562570895266, "Hypokalaemia ": 2.2121733257128118, "Hyponatraemia ": 4.734463974048647, "Hypotension ": 2.1691298000529877, "Infarction ": 7.0628793897563735, "Ischaemia ": 7.462843935712358, "Lip oedema ": 2.67879431892859, "Nephropathy ": 4.016217036440081, "Oedema ": 4.357158260730562, "Oedema peripheral ": 4.973542272350369, "Oliguria ": 6.340160121615348, "Orthostatic hypotension ": 2.4046133224754143, "Periorbital oedema ": 7.242809684882715, "Pharyngeal oedema ": 4.069912583406109, "Proteinuria ": 9.098022280081588, "Pulmonary oedema ": 2.350026519253161, "Renal artery stenosis ": 26.609534044480124, "Renal disorder ": 2.932808354900674, "Renal failure ": 3.170024397725097, "Renal impairment ": 5.808477683964558, "Renin increased ": 277.7919181710361, "Swelling face ": 3.102168043210468, "Swollen tongue ": 3.0068297554335097, "Tachyarrhythmia ": 10.017809356779676, "Tongue oedema ": 3.5821056342397206, "Urine output decreased ": 5.28406996843585, "Wrong technique in product usage process ": 4.4064031125581655} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/913.json new file mode 100644 index 00000000000..7b18de3cf9d --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/913.json @@ -0,0 +1 @@ +{"Aggression ": 5.598032410133944, "Agitation ": 2.640265235905753, "Akathisia ": 204.8978556760539, "Anxiety ": 2.211963657728077, "Drug dose titration not performed ": 523.1307302031682, "Extrapyramidal disorder ": 27.447262021474742, "Insomnia ": 3.079737385748317, "Intentional product use issue ": 9.950928045305458, "Musculoskeletal stiffness ": 3.2188980435166887, "Off label use ": 4.99496807043089, "Parkinsonism ": 25.37826357570688, "Product use in unapproved indication ": 5.227669347252971, "Psychotic disorder ": 11.141630954124706, "Restlessness ": 22.962270011497527, "Salivary hypersecretion ": 21.94485867325364, "Sleep disorder ": 3.797216342306744, "Somnolence ": 2.105369344390159, "Tremor ": 4.376483914792225, "Vision blurred ": 5.436173658770063, "Weight increased ": 5.279379909331964} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/914.json new file mode 100644 index 00000000000..8f19238fa0f --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/914.json @@ -0,0 +1 @@ +{"Abortion induced ": 7.991108066830665, "Adverse event ": 2.837206819599785, "Anaemia ": 18.232024984440663, "Ascites ": 6.4896854900750505, "Asthenia ": 2.379686899766692, "Blood bilirubin increased ": 4.853563273059305, "Blood uric acid increased ": 6.69092896809856, "Cardiac failure ": 2.3480582260699627, "Cholestasis ": 2.0124431549484507, "Cutaneous sarcoidosis ": 70.93362642569758, "Depression ": 3.4147703611952034, "Drug eruption ": 2.320608739067075, "Drug ineffective ": 3.424585574432775, "Dry skin ": 3.171585271804997, "Encephalopathy ": 2.1784189194327657, "Facial paralysis ": 2.117406766195512, "Glomerular filtration rate decreased ": 3.2845716783947854, "Haemoglobin decreased ": 8.788075623712455, "Haemolytic anaemia ": 32.980256969230524, "Hepatic cancer ": 4.745768428083379, "Hepatic cirrhosis ": 6.238490070092362, "Hepatic 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file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/923.json new file mode 100644 index 00000000000..c1f46b42366 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/923.json @@ -0,0 +1 @@ +{"Adrenal insufficiency ": 5.576907565481223, "Ageusia ": 2.823288073136704, "Anosmia ": 2.0925802073220106, "Aphonia ": 30.51226266383044, "Arrhythmia ": 4.282954944881019, "Asphyxia ": 6.067461207006208, "Asthma ": 6.960243949973473, "Asthmatic crisis ": 30.26217356100068, "Atrial fibrillation ": 2.089379859304194, "Bronchitis ": 4.115848754047945, "Bronchospasm ": 3.936047924660193, "Candida infection ": 5.334674592976599, "Catarrh ": 26.42466552980598, "Chest discomfort ": 2.308950098146111, "Choking ": 2.25901327344108, "Chondrocalcinosis pyrophosphate ": 93.25621789278247, "Chronic obstructive pulmonary disease ": 6.213368967533156, 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2.4164460110353843, "Lung neoplasm malignant ": 2.6712682466585123, "Meningitis bacterial ": 78.16649334527607, "Muscle spasms ": 3.577001240784488, "Nasal congestion ": 2.1806746573014086, "Nasal discomfort ": 7.073219053252065, "Nasopharyngitis ": 3.448637728775523, "Oesophageal candidiasis ": 66.59835607258583, "Oral candidiasis ": 16.899030218835332, "Oral discomfort ": 3.715956572333219, "Oral fungal infection ": 38.87649016416324, "Oral pain ": 9.455345454321089, "Oropharyngeal discomfort ": 10.203478245219232, "Oropharyngeal pain ": 5.264133473007273, "Palpitations ": 4.144310787372008, "Pharyngeal disorder ": 17.448855258315934, "Pneumonia ": 4.881886342878162, "Prinzmetal angina ": 44.71070060516731, "Product complaint ": 30.238638022036778, "Product dispensing error ": 5.725191939227428, "Product prescribing issue ": 15.583271941775324, "Product use in unapproved indication ": 4.397950488189578, "Product use issue ": 2.666644847523653, "Productive cough ": 11.25046981692471, 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a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/924.json new file mode 100644 index 00000000000..0aef34a02af --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/924.json @@ -0,0 +1 @@ +{"Acute kidney injury ": 9.6122885636872, "Acute myocardial infarction ": 3.137319701777584, "Acute respiratory distress syndrome ": 27.42513871336273, "Acute respiratory failure ": 26.153673107560103, "Alanine aminotransferase increased ": 25.074898089188316, "Aspartate aminotransferase increased ": 14.829419653001407, "Atrial fibrillation ": 2.2062097818313853, "Blood alkaline phosphatase increased ": 3.67356092029822, "Blood bilirubin increased ": 4.199809219536897, "Blood creatinine increased ": 9.449955324404542, "Blood triglycerides increased ": 9.456787126350733, "Blood urea increased ": 4.529319273436117, "Bradycardia ": 15.6021801938931, "COVID-19 ": 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a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/925.json new file mode 100644 index 00000000000..d6336e14f9b --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/925.json @@ -0,0 +1 @@ +{"Abdominal abscess ": 19.104396055116244, "Abortion spontaneous ": 2.665193559768155, "Abscess ": 7.668284365493086, "Acute myeloid leukaemia ": 2.7029026858615635, "Adverse drug reaction ": 2.427842356575271, "Adverse event ": 2.8093108397832336, "Anal abscess ": 17.675508223543115, "Basal cell carcinoma ": 3.964363311934308, "Bronchitis ": 2.639988332263864, "Candida infection ": 2.821203497001449, "Cellulitis ": 5.585064463023184, "Cholelithiasis ": 2.5652755038623924, "Clostridium difficile infection ": 3.87603304316962, "Colitis ulcerative ": 15.757576647736396, "Colon cancer ": 5.792730116682801, "Crohn's disease ": 19.046555825202717, "Cystitis ": 2.143705703833588, "Cytomegalovirus enterocolitis ": 51.1697142267506, "Cytomegalovirus infection ": 4.11502091357783, "Disseminated tuberculosis ": 41.16119385855462, "Diverticulitis ": 2.292621472783309, "Drug hypersensitivity ": 3.113587102591687, "Drug level decreased ": 7.737995471831603, "Enterobacter infection ": 37.7251054598289, "Exposure during pregnancy ": 6.3994500945255375, "Failed induction of labour ": 228.65543822595637, "Fistula ": 13.194692378923865, "Flushing ": 3.5933305221984795, "Foetal exposure during pregnancy ": 2.8597898514257443, "Frequent bowel movements ": 8.336665048231776, "Fungal infection ": 3.647488837559584, "Gastroenteritis viral ": 6.554932603680343, "Haematochezia ": 3.4020450664099515, "Hidradenitis ": 20.12228760304287, "IgA nephropathy ": 23.9725461664861, "Ileus ": 3.524663454743522, "Infusion related reaction ": 23.21810735084618, "Interstitial lung disease ": 5.1745275017153975, "Intestinal obstruction ": 3.2002196832843595, "Limb injury ": 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"Diarrhoea ": 4.914727876732181, "Flatulence ": 18.670338473500045, "Frequent bowel movements ": 24.48324583090658, "Haematochezia ": 22.43208258586061, "Infection ": 3.401989397300177, "Intentional dose omission ": 161.68423900628736, "Intentional product use issue ": 9.529521865024185, "Lower respiratory tract infection ": 38.60930812577993, "Mucous stools ": 230.5545196447674, "Oropharyngeal pain ": 3.1328507814803235, "Product dose omission issue ": 4.1373207573419375, "Stress ": 19.057788030558893, "Weight decreased ": 8.422461160119319, "Weight increased ": 13.87420717167038} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/927.json new file mode 100644 index 00000000000..aa870bb9241 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/927.json @@ -0,0 +1 @@ +{"Dermatitis contact ": 352.636519738192, "Drug 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5.84545652419119, "Blood glucose decreased ": 5.147961219419824, "Blood glucose increased ": 2.940196085464504, "Depressed level of consciousness ": 3.56984247287949, "Drug interaction ": 8.326404360676671, "Glycosylated haemoglobin increased ": 10.050717719234516, "Hyperglycaemia ": 4.522722420950192, "Hyperkalaemia ": 5.779241485716969, "Hypoglycaemia ": 71.80485213169372, "Hypoglycaemic coma ": 74.39386919495901, "Inappropriate schedule of product administration ": 3.0792771849677902, "Lactic acidosis ": 20.635407602360583, "Loss of consciousness ": 2.572741501472916, "Medication error ": 17.689220306166497, "Metabolic acidosis ": 11.586812331360129, "Myoclonus ": 12.87899500681118, "Pancreatitis acute ": 5.093129475791856, "Sopor ": 44.78243475853676} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/929.json new file mode 100644 index 00000000000..0db37951d11 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/929.json @@ -0,0 +1 @@ +{"Back pain ": 2.934197525506811, "Myalgia ": 2.185215636451157} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/93.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/93.json new file mode 100644 index 00000000000..14675ea5b4c --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/93.json @@ -0,0 +1 @@ +{"Acute kidney injury ": 62.45208257491737} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/930.json new file mode 100644 index 00000000000..75358b1e0fd --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/930.json @@ -0,0 +1 @@ +{"Anaemia ": 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b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/932.json @@ -0,0 +1 @@ +{"Acute respiratory failure ": 2.910069441583389, "Ankle fracture ": 2.846316494998712, "Ascites ": 2.539587105426261, "Atrial flutter ": 2.5521778269132214, "Blood creatine increased ": 5.492073195898689, "Blood disorder ": 4.327913353740692, "Blood iron decreased ": 3.646606378037705, "Blood pressure decreased ": 2.121749830671444, "Body height decreased ": 16.474720539062048, "Bronchitis ": 3.490819053410932, "Cardiac arrest ": 2.9202887497744503, "Cardiac disorder ": 8.737901114492137, "Cardiac failure ": 8.277920213256014, "Cardiac failure chronic ": 7.801808409739831, "Cardiac failure congestive ": 10.945661905532177, "Cardiac valve disease ": 7.127429426350858, "Cataract ": 3.0218606753069643, "Catheter site erythema ": 13.674166652125068, "Catheter site infection ": 13.248195541234816, "Chronic obstructive pulmonary disease ": 8.303919162191285, "Chronic respiratory failure ": 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": 5.742346903072885, "Pain in jaw ": 3.0770392163178446, "Pelvic fracture ": 5.63731821835583, "Pericardial effusion ": 4.303318454889912, "Pleural effusion ": 2.076108301167222, "Pneumonia ": 4.724835403759996, "Pre-existing condition improved ": 18.878108223792363, "Prescribed overdose ": 6.408397397325239, "Product dispensing error ": 2.405952606024619, "Product dose omission issue ": 2.535518816863075, "Product prescribing error ": 2.268025085308202, "Product use in unapproved indication ": 4.1483978827416905, "Product use issue ": 9.70986736753094, "Pulmonary arterial hypertension ": 21.9022734796344, "Pulmonary arterial pressure increased ": 53.59038141320446, "Pulmonary fibrosis ": 6.60847289045028, "Pulmonary haemorrhage ": 2.8356317966961444, "Pulmonary hypertension ": 100.21136138757144, "Pulmonary oedema ": 5.422430920585623, "Pulmonary thrombosis ": 4.929919761129982, "Raynaud's phenomenon ": 3.034748316644695, "Renal disorder ": 4.208431615015384, "Renal failure ": 2.062744533935849, "Respiratory arrest ": 2.112811488233991, "Respiratory distress ": 2.0080961425870107, "Respiratory failure ": 4.632606422577847, "Respiratory tract congestion ": 5.1630924645837615, "Right ventricular failure ": 30.143693775905938, "Scleroderma ": 31.68006842856338, "Sepsis ": 2.286742778420434, "Skin laceration ": 2.469501024733876, "Spinal fracture ": 4.019679794199031, "Sudden death ": 2.141028952056084, "Terminal state ": 21.85705375953049, "Therapeutic response unexpected ": 2.610983391234152, "Upper limb fracture ": 4.382217096822105, "Weight fluctuation ": 5.0709524258068415, "Wrist fracture ": 2.984178247355816} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/933.json new file mode 100644 index 00000000000..7d20ca0558f --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/933.json @@ -0,0 +1 @@ +{"Abdominal distension ": 11.63332394511703, "Abdominal pain ": 5.471351166147669, "Cholecystitis ": 36.47029122276876, "Dehydration ": 8.177235570009085, "Device related infection ": 208.10931976215815, "Intestinal obstruction ": 22.70720852555464, "Pancreatitis ": 5.047738816970853, "Renal impairment ": 2.980405636879917, "Stoma complication ": 3463.132671985337, "Vascular device infection ": 110.71144344430743, "Weight decreased ": 3.7700869099785663, "Weight increased ": 3.848072080381042} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/934.json new file mode 100644 index 00000000000..ec0ce9632ae --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/934.json @@ -0,0 +1 @@ +{"Aphonia ": 70.56324565898791, "Cough ": 5.784124234146119, "Dysphonia ": 53.26779905974566, "Dyspnoea ": 2.112429277585292, "Muscle spasms ": 3.435648955674925, "Product complaint ": 50.18569025613216, "Tachycardia ": 5.822310533764407, "Vision blurred ": 5.499932006837014} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/935.json new file mode 100644 index 00000000000..e769d72da34 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/935.json @@ -0,0 +1 @@ +{"Acute lymphocytic leukaemia ": 15.259900200008904, "Acute myeloid leukaemia ": 10.042940838343702, "Adverse drug reaction ": 2.113249041243876, "Anaemia ": 2.378500468537065, "Atrial fibrillation ": 2.9234328772385787, "Basal cell carcinoma ": 9.633420880079411, "Blood potassium decreased ": 9.9817242664763, "Cardiac disorder ": 2.783740523035974, "Constipation ": 3.3518898502105645, "Cytopenia ": 5.002848039361536, "Deep vein thrombosis ": 2.899802729467226, "Dehydration ": 2.6501426658819045, "Diarrhoea ": 2.5010231672730545, "Disease progression ": 2.3223075201160484, "Drug hypersensitivity ": 2.41295997739638, "Drug reaction with eosinophilia and systemic symptoms ": 4.843724283090128, "Eosinophilia ": 2.187058386980683, "Fall ": 2.152795162491904, "Febrile neutropenia ": 2.7190525650161788, "Fluid retention ": 2.093020117838732, "Full blood count decreased ": 38.37444031328932, "Haemoglobin decreased ": 3.321868162017824, "Human chorionic gonadotropin increased ": 86.19494375627822, "Hypercalcaemia ": 4.231681543534475, "Immune system disorder ": 4.050934355889792, "Infection ": 2.265025484568219, "Laboratory test abnormal ": 5.466539878105095, "Mental status changes ": 2.460071258065713, "Myelodysplastic syndrome ": 18.40211469710746, "Neuropathy peripheral ": 14.733846470626007, "Neutropenia ": 2.3693134696313525, "Neutrophil count decreased ": 5.909111954859764, "Pancytopenia ": 5.8856370015526, "Plasma cell leukaemia ": 107.8712812442313, "Plasma cell myeloma ": 112.17963108683212, "Plasma cell myeloma recurrent ": 118.28309937211156, "Plasmacytoma ": 116.41884360165386, "Platelet count decreased ": 6.849828385037911, "Pneumonia ": 5.757707101418631, "Product dose omission issue ": 2.142745100089854, "Pulmonary thrombosis ": 6.99222647796845, "Rash maculo-papular ": 3.8767426990679006, "Red blood cell count decreased ": 3.9342605766055656, "Renal disorder ": 2.5355254187771683, "Renal failure ": 2.029300591031848, "Renal impairment ": 2.7229367486189404, "Sepsis ": 4.785983102001564, "Septic shock ": 2.863026399981968, "Skin cancer ": 7.364434677399502, "Spinal compression fracture ": 7.863127376414269, "Spinal fracture ": 3.4720645662000407, "Squamous cell carcinoma of skin ": 15.7859665285922, "Staphylococcal infection ": 2.1861837003579865, "Therapy non-responder ": 3.0034351129858945, "Thrombocytopenia ": 2.401947243995723, "Thrombosis ": 5.235736846282176, "Toxic skin eruption ": 2.410586752466516, "Unevaluable event ": 2.471308435465004, "White blood cell count decreased ": 5.201440902574529} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/936.json new file mode 100644 index 00000000000..1c97cb4822f --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/936.json @@ -0,0 +1 @@ +{"Aplastic anaemia ": 156.66864436367123, "Blood bilirubin increased ": 8.652710491189472, "Disease progression ": 4.600762267556851, "Haemoglobin decreased ": 5.9799112277898425, "Liver disorder ": 5.854211892527528, "Neutrophil count decreased ": 8.744216240321132, "Platelet count decreased ": 23.83967818532781, "Product use in unapproved indication ": 11.81408139759398, "Renal impairment ": 5.121604841723337, "Therapeutic product effect incomplete ": 5.53348925887042, "Thrombocytopenia ": 3.175636802090408, "White blood cell count decreased ": 8.223192164994446} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/937.json new file mode 100644 index 00000000000..a70453a85fb --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/937.json @@ -0,0 +1 @@ +{"Abortion spontaneous ": 5.654078537973878, "Acute kidney injury ": 4.136837875356084, "Adverse event ": 4.36861513039756, "Alanine aminotransferase increased ": 2.3407995353814126, "Aspartate aminotransferase increased ": 2.1683863683698887, "Blood alkaline phosphatase increased ": 2.1974001787726, "Blood bilirubin increased ": 29.99183083400323, "Blood bilirubin unconjugated increased ": 91.59487959699156, "Blood creatine phosphokinase increased ": 2.505911739982772, "Blood creatinine increased ": 4.057703972461057, "Blood triglycerides increased ": 4.994795360898335, "Caesarean section ": 59.272017959283446, "Calculus urinary ": 184.74203164834915, "Cholecystitis ": 12.233773176654251, "Cholecystitis acute ": 17.147099570275603, "Cholelithiasis ": 29.8601114088961, "Cholestasis ": 3.2666343409498584, "Cushing's syndrome ": 14.802245477305148, "Diabetes mellitus ": 2.6803133827910326, "Drug interaction ": 2.584605496894881, "Drug resistance ": 10.274192212131634, "Dysphagia ": 2.4733034096747586, "Electrocardiogram QT prolonged ": 3.1487332357555164, "Fanconi syndrome ": 34.118770278916884, "Fanconi syndrome acquired ": 19.91945074203826, "Foetal exposure during pregnancy ": 3.1554473041098103, "Gamma-glutamyltransferase increased ": 2.030095205158305, "Gastrointestinal tube insertion ": 25.148317704360064, "Glomerular filtration rate decreased ": 4.208226432560288, "Gynaecomastia ": 9.93630983269045, "Haematuria ": 2.217126970452264, "Hepatic cirrhosis ": 3.768678234504326, "Hepatic cytolysis ": 14.384184440457895, "Hepatic steatosis ": 3.8311509001919695, "Hepatitis ": 7.748112676319753, "Hepatitis C ": 3.097400349434636, "Hepatitis acute ": 7.743430362215176, "Hepatotoxicity ": 3.263681494975544, "Hip fracture ": 4.0953973062765305, "Hydronephrosis ": 13.064552364159002, "Hyperbilirubinaemia ": 98.03927409503956, "Jaundice ": 56.45262549599393, "Lipoatrophy ": 72.72424495166167, "Lipodystrophy acquired ": 45.35792210685551, "Live birth ": 17.04406533358518, "Liver function test abnormal ": 2.58293801683463, "Maternal exposure during pregnancy ": 5.0191106146855775, "Nephrolithiasis ": 95.4946524093281, "Normal newborn ": 47.3521230043124, "Ocular icterus ": 162.10864387129527, "Osteonecrosis ": 3.5002651700339324, "Pancreatitis ": 5.913890930661339, "Pancreatitis acute ": 3.938583819082288, "Polyneuropathy ": 6.777430396939882, "Pregnancy ": 31.21522719821035, "Proteinuria ": 2.8791696134844176, "Renal colic ": 435.5994258054364, "Renal failure ": 2.8103017615482604, "Renal impairment ": 2.4096596663372702, "Renal pain ": 3.8921833196092233, "Renal tubular necrosis ": 7.764222364023111, "Transaminases increased ": 8.08996473059249, "Twin pregnancy ": 127.26107473158744, "Ventricular tachycardia ": 3.6456469519206514, "Viral load increased ": 38.12423962785753, "Weight increased ": 2.414749165524713, "Yellow skin ": 9.993287100285988} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/938.json new file mode 100644 index 00000000000..8dfffbcb232 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/938.json @@ -0,0 +1 @@ +{"Diarrhoea ": 2.5036642626190755, "Drug interaction ": 6.067452934974008} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/939.json new file mode 100644 index 00000000000..82cbff0f4f3 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/939.json @@ -0,0 +1 @@ +{"Affective disorder ": 2.300511666048243, "Anaemia ": 13.720636164537844, "Anal pruritus ": 9.494457793957295, "Anorectal discomfort ": 6.377334237445123, "Anorectal disorder ": 9.232428133105154, "Aplasia pure red cell ": 27.072688433532356, "Ascites ": 8.615231177692301, "Autoimmune haemolytic anaemia ": 3.329684294857318, "Autoimmune hepatitis ": 4.282821429664738, "Blood bilirubin increased ": 5.363175651413097, "Bone marrow failure ": 2.937554684951757, "Chronic hepatitis C ": 21.21490797082938, "Cryoglobulinaemia ": 40.89345089828407, "Cutaneous sarcoidosis ": 49.87616868919748, "Depression ": 2.288724542443676, "Depressive symptom ": 4.092827579778238, "Dermatitis ": 3.1163940801727037, "Drug ineffective ": 13.123138500513036, "Drug reaction with eosinophilia and systemic symptoms ": 2.9907391295144867, "Encephalopathy ": 3.523350458763207, "Gastric varices ": 38.79697485049733, "Genotype drug resistance test positive ": 69.62172040059913, "Granulocytopenia ": 2.226818705440337, "Graves' disease ": 7.182308576945927, "Haemoglobin abnormal ": 5.890354563154924, "Haemoglobin decreased ": 7.043508002422353, "Haemolysis ": 15.752057155528544, "Haemolytic anaemia ": 16.574781536664425, "Hepatic cancer ": 7.509593228685498, "Hepatic cirrhosis ": 18.211423949475275, "Hepatic encephalopathy ": 15.927670214224351, "Hepatic failure ": 7.293326038199944, "Hepatic fibrosis ": 8.477722510818781, "Hepatic lesion ": 5.493003906844376, "Hepatitis B reactivation ": 14.056526656310446, "Hepatitis C ": 298.6586198673844, "Hepatitis C RNA increased ": 90.82319023474894, "Hepatitis C RNA positive ": 204.29920361086772, "Hepatitis C virus test positive ": 208.4716387124404, "Hepatitis E ": 23.013618978041563, "Hepatocellular carcinoma ": 21.61363963307781, "Hyperbilirubinaemia ": 9.310040241056877, "Hypocalcaemia ": 7.493382316681053, "Hypomagnesaemia ": 12.208683398658328, "Immune system disorder ": 2.439683977107897, "Immune thrombocytopenia ": 2.3115701136270284, "Jaundice ": 3.4760911986690397, "Leukopenia ": 3.0724237219492827, "Liver transplant ": 23.68568270437797, "Liver transplant rejection ": 12.654757578857504, "Lymphopenia ": 3.032454403605515, "Mania ": 2.823502289625839, "Mental status changes ": 2.2090090052939235, "Mitochondrial toxicity ": 11.496602397107832, "Oesophageal varices haemorrhage ": 26.03871474924258, "Pancytopenia ": 2.9024323561220244, "Paranoia ": 2.147162603587857, "Pathogen resistance ": 3.805979651383172, "Personality change ": 2.737295244151301, "Polydipsia ": 3.9943487712233257, "Polyuria ": 2.3949521372821843, "Porphyria non-acute ": 28.203000947941906, "Portal hypertension ": 8.161965845362309, "Portal vein thrombosis ": 11.541880933481238, "Proctalgia ": 4.497240026359802, "Product use issue ": 2.106283945635109, "Psychotic disorder ": 3.5022921063778685, "Pulmonary arterial hypertension ": 2.3689584657338605, "Red blood cell count decreased ": 2.548765900302668, "Remission not achieved ": 59.43979644407972, "Renal impairment ": 2.952741410901281, "Retinopathy ": 9.647398177445456, "Sarcoidosis ": 35.234136354622734, "Skin fissures ": 3.4608382545625664, "Skin laceration ": 3.022576464560005, "Spontaneous bacterial peritonitis ": 21.08094225289485, "Therapy cessation ": 3.754166716740325, "Therapy non-responder ": 4.367961425666942, "Transfusion ": 6.069081172467718, "Treatment failure ": 30.163825690657102, "Treatment noncompliance ": 3.250176080624052, "Type 1 diabetes mellitus ": 3.659968100447061, "Unevaluable event ": 3.18860014779985, "Varices oesophageal ": 13.629255882454062, "Viral load increased ": 13.45464430674092, "Viral mutation identified ": 28.356824525381988, "Virologic failure ": 62.376829354287736} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/94.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/94.json new file mode 100644 index 00000000000..a42250ce6dc --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/94.json @@ -0,0 +1 @@ +{"Completed suicide ": 158.5298852551079} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/940.json new file mode 100644 index 00000000000..475ac26954e --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/940.json @@ -0,0 +1 @@ +{"Alanine aminotransferase increased ": 8.865599627801314, "Anaemia ": 2.652907608378116, "Aspartate aminotransferase increased ": 9.142394708369558, "Blood alkaline phosphatase increased ": 4.309969433314161, "Blood bilirubin increased ": 4.362074356800702, "Blood creatinine increased ": 2.0874397691908726, "Bone lesion ": 106.27735925697556, "Bone pain ": 2.2162236238182427, "Breast cancer ": 11.848224408275744, "Breast cancer metastatic ": 106.076078243657, "Breast cancer recurrent ": 24.06288820845183, "Breast mass ": 36.2931240431416, "Carbohydrate antigen 15-3 increased ": 358.6665543722972, "Carcinoembryonic antigen increased ": 39.950177391668255, "Disease progression ": 3.5577342865313857, "Electrocardiogram QT prolonged ": 19.127989752419097, "Febrile neutropenia ": 2.6518169682372834, "Gamma-glutamyltransferase increased ": 3.1493419256252144, "Granulocytopenia ": 6.4494456038953, "Haematocrit decreased ": 4.957351605025616, "Haematotoxicity ": 19.478325362592496, "Haemoglobin decreased ": 3.207140828356476, "Hepatic enzyme increased ": 2.888928198072392, "Hepatic failure ": 3.4202275596948484, "Hepatic lesion ": 24.1811488612435, "Hepatic steatosis ": 3.3403508294835342, "Hepatitis ": 2.631150189797532, "Hepatotoxicity ": 42.37642320431733, "Hormone receptor positive HER2 negative breast cancer ": 739.6284857264747, "Hot flush ": 2.758221051930096, "Hypertransaminasaemia ": 14.751527832335034, "Leukopenia ": 15.258175669243291, "Liver function test increased ": 3.722892574065247, "Liver injury ": 2.180673050781036, "Malignant neoplasm progression ": 17.327820122738164, "Metastases to bone ": 77.19685287946722, "Metastases to central nervous system ": 6.822928870819823, "Metastases to liver ": 44.954693367645305, "Metastases to lung ": 36.50779916579864, "Metastases to lymph nodes ": 40.90150870083818, "Metastases to pleura ": 69.54439858823935, "Metastases to spine ": 37.56694829658316, "Metastasis ": 18.504186471736244, "Neutropenia ": 38.78440878646156, "Neutrophil count decreased ": 6.38435292781037, "PIK3CA-activated mutation ": 139.72286085065116, "Pleural effusion ": 4.336217119998718, "Pneumonitis ": 4.221716719579039, "Pulmonary mass ": 5.1817882879946335, "Skin toxicity ": 10.701557439940547, "Therapeutic response decreased ": 2.8099632725825394, "Therapy partial responder ": 45.722913034238296, "Thrombocytopenia ": 2.557097466119405, "Transaminases increased ": 5.982256929761117, "Tumour marker increased ": 18.321001091922437, "Vitiligo ": 31.45282931179806, "White blood cell count decreased ": 5.349684788091665} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/941.json new file mode 100644 index 00000000000..57bac946c7a --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/941.json @@ -0,0 +1 @@ +{"Adverse reaction ": 52.27602465770154, "Agranulocytosis ": 7.717355657915041, "Amyotrophic lateral sclerosis ": 287.1360725659436, "Angioedema ": 2.397005643615922, "C-reactive protein increased ": 5.569495621042735, "Condition aggravated ": 2.529703687805848, "Death ": 4.225347330789885, "Disease progression ": 19.985820636324505, "Dysphagia ": 10.107918984872065, "Gastric fistula ": 847.6445785237527, "Hepatic enzyme increased ": 2.8071925575445054, "Interstitial lung disease ": 10.14147402809956, "Motor neurone disease ": 1354.1392518161315, "Oxygen saturation decreased ": 4.895565807919141, "Pancreatitis ": 6.768214897223107, "Pancreatitis acute ": 12.25409631709886, "Renal impairment ": 2.1193589760876006, "Respiratory failure ": 3.7773754379097406, "Speech disorder ": 8.068271285287935} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/942.json new file mode 100644 index 00000000000..c1412653706 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/942.json @@ -0,0 +1 @@ +{"Condition aggravated ": 2.104734489129125, "Death ": 17.58785499525715, "Disease progression ": 10.671788302266242, "Drug interaction ": 2.727567420568221, "Gastrointestinal disorder ": 4.771925269578914, "Interstitial lung disease ": 11.600384773928296, "Pancreatitis acute ": 15.922121402782386} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/943.json new file mode 100644 index 00000000000..638c15ca9c4 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/943.json @@ -0,0 +1 @@ +{"Abnormal weight gain ": 6.005971472584468, "Abortion induced ": 2.4732068224866106, "Abscess ": 2.276288007385868, "Acne ": 49.621101479197925, "Adenocarcinoma of colon ": 8.737161144514905, "Adverse drug reaction ": 4.229208421116481, "Alanine aminotransferase increased ": 2.3136299291816167, "Alopecia areata ": 3.372158443839574, "Ankle fracture ": 2.066262241425713, "Ankylosing spondylitis ": 2.816111474897571, "Aphthous ulcer ": 4.783314784655471, "Arthritis ": 3.250936412412874, "Arthritis bacterial ": 3.678470300077306, "Autoimmune disorder ": 2.607852776472039, "Basal cell carcinoma ": 3.5212538288788267, "Blood cholesterol increased ": 5.8492789731362, "Blood creatine phosphokinase increased ": 9.48199002843258, "Blood iron decreased ": 3.957637095227268, "Blood triglycerides increased ": 6.250642925383463, "Breast cancer female ": 11.749656230069142, "C-reactive protein increased ": 3.308175966140888, "Cellulitis ": 2.463731447863826, "Cerebrovascular accident ": 2.494039019276256, "Clostridium difficile infection ": 2.665947935295035, "Colectomy ": 17.32529223965676, "Colitis ischaemic ": 2.001933340200184, "Colitis ulcerative ": 7.013436005506558, "Colon cancer ": 2.843256549723816, "Coronavirus infection ": 10.883178419716408, "Crohn's disease ": 3.5153066016908654, "Cutaneous T-cell lymphoma ": 20.339623801921945, "Cytomegalovirus colitis ": 8.032653373812398, "Cytomegalovirus infection ": 2.3235527049488804, "Deep vein thrombosis ": 4.713727064858936, "Dermatitis acneiform ": 12.996695656558094, "Dermatitis atopic ": 76.47226426717344, "Diverticulitis ": 5.199960889352604, "Diverticulitis intestinal perforated ": 95.70263287671716, "Diverticulum ": 2.5944385848836133, "Diverticulum intestinal haemorrhagic ": 6.458060957101545, "Eczema ": 3.2567135673373167, "Eczema herpeticum ": 258.34599891787883, "Embolism ": 4.760004513842372, "Embolism venous ": 15.404675622541552, "Erysipelas ": 4.368873185481797, "Erythema nodosum ": 3.333841955523747, "Faecal calprotectin increased ": 23.452166121700063, "Folliculitis ": 4.6578291969573975, "Foot deformity ": 2.1604749295277226, "Foot operation ": 5.491155492377541, "Frequent bowel movements ": 3.701705741691852, "Frustration tolerance decreased ": 2.611825415051352, "Furuncle ": 5.102242323332209, "Gastrointestinal perforation ": 25.263895824690486, "General symptom ": 11.243500433951178, "Genital herpes ": 19.003009222257848, "Genital herpes zoster ": 70.67250293088274, "Gingival pain ": 6.82892240979074, "Haematocrit decreased ": 2.144471334451928, "Hepatitis B ": 3.8459932689346337, "Hepatitis E ": 20.70950238902325, "Herpes ophthalmic ": 36.00855282893569, "Herpes simplex ": 17.119894279312625, "Herpes virus infection ": 21.3461419727408, "Herpes zoster ": 10.37854035603726, "Herpes zoster disseminated ": 15.486438901225457, "High density lipoprotein increased ": 23.937290253463665, "Hordeolum ": 11.39450420949474, "Hypercholesterolaemia ": 5.744124232022465, "Ileostomy ": 45.64470545883065, "Immunodeficiency ": 4.524245392290687, "Immunosuppression ": 8.604682647038587, "Impetigo ": 19.33030849576726, "Infection ": 2.3340980809170984, "Inflammation ": 2.6446323869119075, "Inflammatory bowel disease ": 4.429214628484195, "Inflammatory marker increased ": 3.874335321154836, "Intervertebral disc protrusion ": 2.8548079335450582, "Intestinal perforation ": 6.048539483244509, "Joint arthroplasty ": 14.761714643336084, "Joint dislocation ": 3.87826984792312, "Joint effusion ": 3.820260722652491, "Joint lock ": 11.360775186187848, "Joint swelling ": 2.332162037565584, "Knee arthroplasty ": 2.4267527637859208, "Knee operation ": 14.051546388580569, "Laboratory test abnormal ": 3.9547856204719793, "Large intestine perforation ": 3.1395876477275526, "Lichenification ": 34.57120774683536, "Lipids increased ": 25.13823522661907, "Liver abscess ": 5.309696110515334, "Liver function test increased ": 3.485373640472775, "Loss of therapeutic response ": 12.81877212950778, "Low density lipoprotein increased ": 33.65583573680853, "Lung neoplasm malignant ": 2.745309089353502, "Lung opacity ": 4.900077487906754, "Lymphocyte count decreased ": 2.376827763762872, "Lymphocyte count increased ": 5.071809767424735, "Lymphoma ": 5.861253074952829, "Lymphopenia ": 3.80303966770919, "Malabsorption ": 5.98398775184608, "Malignant melanoma ": 3.870643412967511, "Meningitis ": 3.885957320941921, "Middle insomnia ": 3.581925439903827, "Mobility decreased ": 2.138089171974596, "Mouth ulceration ": 2.082510743071653, "Musculoskeletal disorder ": 4.766405364026517, "Neoplasm malignant ": 2.233107415963276, "Nerve compression ": 3.7905352177558, "Neuroendocrine carcinoma of the skin ": 27.869252458487264, "Ophthalmic herpes zoster ": 9.899244154207254, "Oral candidiasis ": 2.5810019956608703, "Oral herpes ": 10.802274084733094, "Organising pneumonia ": 2.4237319910097623, "Osteoarthritis ": 2.8362530455011776, "Ostomy bag placement ": 441.3242238122656, "Overweight ": 3.681188859816153, "Pain of skin ": 2.364682603535332, "Papilloma viral infection ": 6.841144726359089, "Papule ": 2.0767886461909986, "Phlebitis ": 4.018172399913326, "Platelet count increased ": 4.8985689135926105, "Pneumocystis jirovecii pneumonia ": 9.514856509044794, "Pneumonia bacterial ": 3.905681666530848, "Polyarthritis ": 3.702505109587792, "Portal vein thrombosis ": 4.602849813601846, "Post herpetic neuralgia ": 3.496675873382596, "Post procedural complication ": 2.96557265258614, "Post procedural infection ": 5.919483272612193, "Product residue present ": 50.648782418079904, "Psoriasis ": 3.5421088835381243, "Psoriatic arthropathy ": 3.210766460606365, "Pulmonary embolism ": 7.159614062367764, "Pulmonary thrombosis ": 3.5624446881862863, "Purulent discharge ": 6.360660905819318, "Pustule ": 8.548560022045779, "Rash pustular ": 5.641788329028064, "Red blood cell sedimentation rate increased ": 2.4447904677894483, "Respiratory tract infection ": 4.934694337120175, "Retinal artery occlusion ": 3.309424599762452, "Retinal detachment ": 2.407278713548162, "Retinal vein occlusion ": 5.941969111206735, "Rheumatic disorder ": 6.098823659678434, "Rheumatoid arthritis ": 7.204183789109653, "Rosacea ": 29.57627113436828, "Scab ": 2.038828821780289, "Semen discolouration ": 289.0849879776245, "Skin cancer ": 3.940254848627724, "Skin disorder ": 4.212365609405509, "Skin lesion ": 3.20011956906552, "Skin plaque ": 4.707851274598522, "Sluggishness ": 2.085762982981905, "Spinal compression fracture ": 2.403045118314476, "Spinal fracture ": 2.7059764409540894, "Spinal operation ": 5.40908461664921, "Spinal pain ": 2.1086057426790688, "Spinal stenosis ": 2.9068184478525096, "Squamous cell carcinoma ": 2.952690517913461, "Squamous cell carcinoma of skin ": 6.275978905977544, "Subcutaneous abscess ": 4.220845161687265, "Superficial vein thrombosis ": 2.486406732099631, "Superinfection ": 11.26687674351851, "Surgery ": 3.3347755421198317, "Suspected COVID-19 ": 2.5153569406371306, "Synovitis ": 4.321514368197263, "Therapeutic product effect decreased ": 4.722361518391275, "Therapeutic product effect incomplete ": 4.442196321109064, "Therapeutic response shortened ": 4.188111256097998, "Thrombosis ": 3.384953273007905, "Tongue neoplasm malignant stage unspecified ": 14.0273953179269, "Tonsillitis ": 3.632839904345888, "Tooth abscess ": 2.9059059122796618, "Transaminases increased ": 3.353007119714836, "Tuberculosis ": 4.998170287611517, "Ulcer ": 5.353798710246716, "Unevaluable event ": 6.675917046014343, "Upper respiratory tract infection ": 2.8972700512679066, "Varicella zoster virus infection ": 9.929327595907507, "Venous thrombosis ": 3.066795475760269, "Venous thrombosis limb ": 7.655034469053054, "Vitamin D decreased ": 4.118669329111923, "Vulvovaginal mycotic infection ": 3.221663923383557, "Weight increased ": 5.827381934297904} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/944.json new file mode 100644 index 00000000000..709672769db --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/944.json @@ -0,0 +1 @@ +{"Bradycardia ": 17.29285774469415, "Condition aggravated ": 9.511550497386043, "Dyspnoea exertional ": 40.80273422367407, "Hypotension ": 8.0888185020458, "Left-to-right cardiac shunt ": 20394.860412082395, "Pulmonary hypertension ": 102.00807033669888, "Therapeutic product effect incomplete ": 20.75869366568164, "Vascular resistance pulmonary decreased ": 79946.97217693867} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/945.json new file mode 100644 index 00000000000..e7f03407f74 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/945.json @@ -0,0 +1 @@ +{"Crohn's disease ": 54.517793726689206, "Drug ineffective ": 2.0670720124293824, "Off label use ": 12.406339922583518, "Psoriasis ": 64.94692932419719, "Psoriatic arthropathy ": 24.8556723405198} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/946.json new file mode 100644 index 00000000000..011a53b95ba --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/946.json @@ -0,0 +1 @@ +{"Abnormal behaviour ": 7.068079384800062, "Acute psychosis ": 17.990680499979902, "Adverse drug reaction ": 3.012132011989039, "Aggression ": 4.053013405625042, "Agitation ": 5.633948181427527, "Akathisia ": 5.32539636822857, "Alanine aminotransferase increased ": 2.106335512013991, "Aspartate aminotransferase increased ": 2.868585812657826, "Asphyxia ": 7.301962654714328, "Ataxia ": 5.013150284737163, "Blood creatine phosphokinase increased ": 3.7414610368613226, "Blood prolactin increased ": 22.948509763138265, "Bradykinesia ": 16.140439068982165, "Brain injury ": 6.020931689875798, "Catatonia ": 22.139566954908773, "Circulatory collapse ": 2.420592657576212, "Cognitive disorder ": 2.2310978319221086, "Confusional state ": 3.192707645869039, "Cyanosis ": 3.040803128395842, "Delirium ": 3.1082039489478555, "Dementia ": 2.26469208410736, "Depressed level of consciousness ": 14.849125585452851, "Drug interaction ": 8.208174958199752, "Drug level increased ": 2.6775494459026072, "Dysarthria ": 4.998529316077903, "Dyskinesia ": 3.3110846549008937, "Dystonia ": 11.700979329501202, "Emotional disorder ": 6.337126418785396, "Encephalopathy ": 4.175079612766444, "Extrapyramidal disorder ": 35.78011921299647, "Feeling abnormal ": 3.492269262438848, "Galactorrhoea ": 10.581923308275991, "Generalised tonic-clonic seizure ": 2.0941628084335417, "Gynaecomastia ": 14.851192660703886, "Hallucination, auditory ": 14.608692375920151, "Hallucination, visual ": 5.512040834318139, "Hyperammonaemia ": 8.665817939994946, "Hyperprolactinaemia ": 25.00432169848642, "Hyperreflexia ": 22.62011857434509, "Hypertonia ": 6.812703460666097, "Hypothermia ": 4.774712848697141, "Hypoxia ": 3.931237559423455, "Irritability ": 2.9416183713819666, "Lethargy ": 7.957249694101176, "Leukocytosis ": 3.5071704222147417, "Mania ": 8.287095506684738, "Mental disorder ": 2.4171961297892444, "Mental impairment ": 2.661810997863701, "Mental status changes ": 4.162468380293945, "Metabolic acidosis ": 2.7703926846867457, "Mood altered ": 3.062818842060969, "Mood swings ": 3.8223233951197466, "Movement disorder ": 2.581078911780785, "Multiple drug therapy ": 41.009342614502486, "Muscle rigidity ": 21.58596416363122, "Myoclonus ": 10.635696612364184, "Neuroleptic malignant syndrome ": 17.142879721773358, "Neurotoxicity ": 4.223653893050045, "Obesity ": 5.738143285086417, "Orthostatic hypotension ": 2.4388633667419204, "Panic disorder ": 15.532924596578226, "Paranoia ": 9.838709216430772, "Parkinsonism ": 19.074003955242866, "Patient elopement ": 82.56907334482011, "Pneumonia aspiration ": 2.329287172265972, "Priapism ": 54.40247395563022, "Product use in unapproved indication ": 2.372031556906676, "Psychotic disorder ": 8.139262409338215, "Respiratory depression ": 37.90971896698693, "Restlessness ": 2.8224608212948032, "Rhabdomyolysis ": 2.862704163174849, "Salivary hypersecretion ": 30.957771260479024, "Schizophrenia ": 11.156527561526175, "Sedation ": 16.58734862341142, "Sedation complication ": 11.540622230250191, "Self-destructive behaviour ": 19.716546210210144, "Serotonin syndrome ": 8.687994599418479, "Sinus tachycardia ": 3.683198345001944, "Somnolence ": 2.3903874744104963, "Suicidal ideation ": 4.842102569902428, "Suicide attempt ": 2.150143598807894, "Tachypnoea ": 4.637826717789036, "Tardive dyskinesia ": 11.535893240526423, "Toxicity to various agents ": 7.321933732415831, "Treatment noncompliance ": 2.541804564868382, "Tremor ": 2.283729310114632, "Urinary incontinence ": 4.349393433948786, "Weight increased ": 5.454828894596825, "Wrong patient received product ": 19.8768074989713} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/947.json new file mode 100644 index 00000000000..e8f2295b5bb --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/947.json @@ -0,0 +1 @@ +{"Diarrhoea ": 11.158261065504544} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/948.json new file mode 100644 index 00000000000..2c8828681a5 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/948.json @@ -0,0 +1 @@ +{"Adrenal insufficiency ": 47.04643325988366, "Adrenal suppression ": 187.3555018347998, "Cortisol decreased ": 88.51905521954818, "Cushing's syndrome ": 475.6644080728068, "Cushingoid ": 123.73437360705206, "Drug interaction ": 31.49152197950092, "Drug level increased ": 12.3942102715817, "Ergot poisoning ": 787.4455344018598, "Neutropenia ": 2.162577930158074, "Osteonecrosis ": 2.06848121012976, "Osteoporosis ": 2.257155108783413, "Pancreatitis ": 3.286040564070988, "Pseudo Cushing's syndrome ": 570.5118041624851, "Secondary adrenocortical insufficiency ": 391.7042329091548, "Skin striae ": 159.8712553717871, "Weight increased ": 4.989211518431254} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/949.json new file mode 100644 index 00000000000..c31fa025db1 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/949.json @@ -0,0 +1 @@ +{"Acute hepatic failure ": 6.380704945802501, "Acute hepatitis B ": 16.793412356686332, "Acute lung injury ": 41.44434942048056, "Acute myeloid leukaemia ": 4.829202071174824, "Acute respiratory distress syndrome ": 2.666724896224331, "Adenovirus infection ": 4.6571297170754455, "Agranulocytosis ": 5.450813582679331, "Anti-cyclic citrullinated peptide antibody positive ": 2.90581819205919, "Arthropathy ": 2.5598916915263383, "Arthropod bite ": 3.4820277293417083, "Aspergillus infection ": 4.618573352950267, "Autoimmune haemolytic anaemia ": 4.599631440746169, "B-cell lymphoma ": 7.021131089419899, "B-cell lymphoma recurrent ": 62.351405419933656, "B-lymphocyte count decreased ": 30.99748987430866, "Bacteraemia ": 5.978353536446752, "Bacterial infection ": 2.089840712621517, "Bacterial sepsis ": 5.157489484408598, "Basal cell carcinoma ": 2.7824853779707857, "Bicytopenia ": 23.16369151093126, "Blood lactate dehydrogenase increased ": 3.138886849400416, "Blood pressure diastolic abnormal ": 116.12787142112695, "Blood pressure diastolic decreased ": 24.942121355388263, "Blood pressure diastolic increased ": 32.839848477148415, "Blood pressure fluctuation ": 12.25740607277717, "Blood pressure systolic abnormal ": 148.3243939568738, "Blood pressure systolic increased ": 20.00641794514234, "Body temperature decreased ": 6.60255723606904, "Bone disorder ": 2.18311665541804, "Bone marrow failure ": 3.5784237601147124, "Bronchiectasis ": 2.3817919395280085, "Bronchopulmonary aspergillosis ": 4.476486025026864, "Bursitis ": 2.1205709233207566, "C-reactive protein increased ": 2.206613969590191, "COVID-19 pneumonia ": 8.646541050166391, "Candida infection ": 2.4289256053844577, "Cardiomyopathy ": 2.342071531028529, "Cardiotoxicity ": 2.8137131196543685, "Castleman's disease ": 26.35375761621817, "Cellulitis ": 2.4702574857767168, "Central nervous system lymphoma ": 22.012182381995828, "Cerebral aspergillosis ": 25.21120750732176, "Cerebral disorder ": 3.164397343980253, "Cervix disorder ": 23.69189430293826, "Chronic lymphocytic leukaemia ": 22.212136918986264, "Chronic lymphocytic leukaemia recurrent ": 33.993158171978635, "Chronic myeloid leukaemia ": 2.834794600584142, "Clumsiness ": 5.999418821751212, "Contraindicated product administered ": 2.045184107753752, "Cystitis haemorrhagic ": 2.4269923112699123, "Cytokine release syndrome ": 3.121974456147579, "Cytomegalovirus chorioretinitis ": 14.404498995273988, "Cytomegalovirus infection ": 4.506930796395857, "Cytomegalovirus infection reactivation ": 2.3437168626612386, "Cytomegalovirus viraemia ": 5.029090110871184, "Cytopenia ": 9.10827779289287, "Dental caries ": 2.65942640598749, "Device dislocation ": 3.755954533019195, "Diffuse large B-cell lymphoma ": 33.001508828321526, "Diffuse large B-cell lymphoma recurrent ": 65.52134446401145, "Diffuse large B-cell lymphoma refractory ": 53.69899947678527, "Diffuse large B-cell lymphoma stage IV ": 49.54207641358289, "Disease progression ": 5.858499965834046, "Disease recurrence ": 2.619232298635682, "Dislocation of vertebra ": 3.152980222828206, "Disseminated Bacillus Calmette-Guerin infection ": 77.00236255179288, "Drug effective for unapproved indication ": 2.858437953108741, "Drug hypersensitivity ": 4.54796354377316, "Drug intolerance ": 2.0212168741163885, "Duodenal ulcer perforation ": 4.016529489487501, "Ear infection ": 2.606658696923169, "Ear pruritus ": 9.56806695868124, "Ejection fraction decreased ": 2.036429819355835, "Endocarditis ": 2.1507371414184453, "Enterococcal infection ": 3.663295371341497, "Epstein-Barr virus infection ": 4.091934294376123, "Eye infection ": 4.709715159127006, "Facet joint syndrome ": 2.186981202173793, "Febrile neutropenia ": 16.070047843491135, "Fibromyalgia ": 2.2365918639676705, "Finger deformity ": 8.287996516877763, "Follicular lymphoma ": 39.17102440589634, "Folliculitis ": 2.685735105547101, "Foot fracture ": 2.3166968197252857, "Granulocyte count decreased ": 21.691994480770685, "Granulocytopenia ": 6.603366785039535, "Haematotoxicity ": 7.216792466840529, "Hand deformity ": 2.625865196199946, "Heart rate decreased ": 7.341668912577151, "Heart rate increased ": 2.1052827178991427, "Helicobacter infection ": 3.749615427759577, "Hepatitis B ": 16.74158960573574, "Hepatitis B reactivation ": 83.26249184874018, "Herpes simplex ": 2.654232040550954, "Hodgkin's disease ": 15.236068865879425, "Hordeolum ": 6.244216407819965, "Humoral immune defect ": 238.6522128619549, "Hypoalbuminaemia ": 4.177717973622568, "Hypogammaglobulinaemia ": 26.44616565656873, "Ill-defined disorder ": 4.5627170500453085, "Immune reconstitution inflammatory syndrome ": 3.4521560984508524, "Immunodeficiency ": 2.85650044819195, "Immunoglobulins decreased ": 13.363436198413766, "Immunosuppression ": 5.795676848269999, "Impaired healing ": 3.051832204922506, "Infection ": 3.559668631478021, "Infusion related reaction ": 9.151837978951018, "Intentional product use issue ": 3.1498801228938698, "Interstitial lung disease ": 5.822639004511467, "Intestinal perforation ": 4.144391115874987, "JC virus infection ": 18.671698031993053, "Joint swelling ": 2.604745402270192, "Klebsiella bacteraemia ": 16.87453514401889, "Klebsiella infection ": 5.662584519829539, "Klebsiella sepsis ": 14.637567154789684, "Leukopenia ": 3.784945212991589, "Ligament sprain ": 6.044906870906838, "Lip disorder ": 17.210922557143547, "Localised infection ": 4.079913037962451, "Low birth weight baby ": 2.10237602363072, "Lung opacity ": 2.0082885858915183, "Lymphocyte count decreased ": 6.777745947608089, "Lymphocytosis ": 4.593567857445642, "Lymphoma ": 4.67503546461384, "Lymphopenia ": 5.878505093663969, "Lymphoproliferative disorder ": 6.171210265561445, "Mantle cell lymphoma ": 29.88309948155111, "Mantle cell lymphoma recurrent ": 27.407653036525947, "Marginal zone lymphoma recurrent ": 323.8160277764217, "Maternal exposure timing unspecified ": 2.9237512487509574, "Metastasis ": 2.3220098721552054, "Mucosal inflammation ": 2.704544466110942, "Muscle injury ": 2.309407024990068, "Myasthenia gravis ": 2.3522965180062028, "Myelodysplastic syndrome ": 7.532113316446473, "Myelodysplastic syndrome with single lineage dysplasia ": 21.14767341963071, "Myelosuppression ": 17.771099440325496, "Nasopharyngitis ": 2.7828605520688083, "Neutropenia ": 6.417052210893263, "Neutropenic infection ": 17.668595973878624, "Neutropenic sepsis ": 22.872962403719743, "Neutrophil count decreased ": 12.74424517965492, "Neutrophil count increased ": 2.9620141285114108, "Nodule ": 3.532314893811435, "Non-Hodgkin's lymphoma ": 5.880504835299436, "Non-Hodgkin's lymphoma recurrent ": 60.31046632054312, "Noninfective encephalitis ": 21.410416223711024, "Oedema ": 2.6931213804520997, "Oesophageal candidiasis ": 4.129937549063519, "Off label use ": 2.1871226582578545, "Onychomycosis ": 4.016773770975223, "Oxygen saturation decreased ": 5.994611888015808, "Pancytopenia ": 4.400352041460621, "Pharyngeal ulceration ": 12.82537123462368, "Platelet count decreased ": 2.387845084975321, "Platelet disorder ": 5.046152382377004, "Pneumocystis jirovecii pneumonia ": 33.200442139688704, "Pneumonia ": 3.35969180175371, "Pneumonia bacterial ": 3.740429481927064, "Pneumonia cytomegaloviral ": 6.441163796596672, "Pneumonia fungal ": 4.613207032307488, "Pneumonia viral ": 4.361100585922058, "Polymyositis ": 8.943281330508277, "Poor venous access ": 15.933221914564468, "Post transplant lymphoproliferative disorder ": 6.6189281996480895, "Posterior reversible encephalopathy syndrome ": 3.472420200296689, "Procedural haemorrhage ": 4.991470222230597, "Product use in unapproved indication ": 2.283857454161457, "Productive cough ": 2.3197037309607724, "Progressive multifocal leukoencephalopathy ": 19.67093241726139, "Pseudomonas infection ": 3.249586449277101, "Pulmonary toxicity ": 10.935116694941216, "Recurrent cancer ": 10.24114600103334, "Remission not achieved ": 133.02310288664484, "Respiratory tract infection ": 2.8710002115688544, "Rheumatoid arthritis ": 2.361410234758249, "Rheumatoid factor positive ": 2.055448615396435, "Richter's syndrome ": 50.98188402297676, "Second primary malignancy ": 7.716291209636893, "Sepsis ": 3.1868621999115248, "Septic shock ": 3.886442055664939, "Sinusitis ": 2.604384826438487, "Skin laceration ": 2.005542838379549, "Small intestinal obstruction ": 2.8814229693865765, "Squamous cell carcinoma ": 2.21085086764347, "Staphylococcal bacteraemia ": 4.137839760243665, "Staphylococcal sepsis ": 4.76105818679071, "Synovitis ": 2.6140392681667413, "Therapy non-responder ": 2.4078835683234185, "Therapy partial responder ": 9.660154056827263, "Throat irritation ": 2.592024034163344, "Thrombocytopenia ": 2.621037791284936, "Tooth abscess ": 2.464687561731058, "Tooth disorder ": 2.513779430353284, "Tooth infection ": 5.137408110558667, "Traumatic lung injury ": 6.143339557167915, "Tumour lysis syndrome ": 20.2613060708329, "Upper limb fracture ": 2.6420945475793345, "Varicella zoster virus infection ": 4.057886656531585, "Viral upper respiratory tract infection ": 8.74165906153246, "Wheezing ": 2.3492137366699177, "White blood cell count decreased ": 9.566078493125795, "Wound infection ": 2.018068702556373} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/95.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/95.json new file mode 100644 index 00000000000..bcdbda1e528 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/95.json @@ -0,0 +1 @@ +{"Completed suicide ": 93.52661870911469} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/950.json new file mode 100644 index 00000000000..577913e92ab --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/950.json @@ -0,0 +1 @@ +{"Acute kidney injury ": 2.245188769291827, "Angina pectoris ": 4.64321205926022, "Aphasia ": 2.8177158397889865, "Atrial fibrillation ": 3.5577553749959256, "Blood creatine phosphokinase increased ": 2.569324450883228, "Blood urea increased ": 8.15278520847671, "Bradycardia ": 3.019722875778368, "Brain natriuretic peptide increased ": 33.519517355124016, "Cardiac failure ": 3.618114900962575, "Cardiac failure congestive ": 2.6077167924750766, "Cardiac murmur ": 12.048183436293035, "Cardio-respiratory arrest ": 2.7018355195017514, "Cerebral haemorrhage ": 2.6629144268565463, "Chronic obstructive pulmonary disease ": 3.839103435986262, "Circulatory collapse ": 3.322376805809953, "Completed suicide ": 13.677973024852404, "Deep vein thrombosis ": 4.7615426551943605, "Delirium ": 4.953983993032037, "Disorientation ": 2.700465605601525, "Drug interaction ": 10.239689970945657, "Drug-induced liver injury ": 2.306312553190929, "Dyspnoea exertional ": 3.12858777321857, "Epistaxis ": 3.593364127299268, "Gastrointestinal haemorrhage ": 6.93947588683711, "Glycosylated haemoglobin increased ": 5.690617275314498, "Haematemesis ": 3.800712710131725, "Haematuria ": 4.782536841380658, "Haemoptysis ": 6.144725613183323, "Haemorrhage ": 3.931876757998063, "Hemiparesis ": 6.69434751972392, "Intentional overdose ": 7.056958957338947, "International normalised ratio increased ": 4.366425158860022, "Labelled drug-drug interaction medication error ": 11.36288257218647, "Melaena ": 7.669519975721385, "Myoglobin blood increased ": 44.567448222234816, "Nasal congestion ": 3.8404634944945606, "Oedema peripheral ": 4.082292613670128, "Oxygen saturation decreased ": 2.84112514037655, "Productive cough ": 3.8019640934753776, "Pulmonary embolism ": 4.852968068291953, "Rales ": 15.35023473892008, "Red cell distribution width increased ": 32.451923574487544, "Rhabdomyolysis ": 2.330031726648471, "Suicide attempt ": 2.211895002782046, "Suspected suicide ": 82.23291132768826, "Tachypnoea ": 5.382116393626405, "Thrombosis ": 5.392012464658995, "Toxicity to various agents ": 8.797043638871614, "Troponin increased ": 10.404494787869009, "Upper gastrointestinal haemorrhage ": 8.643328108856178, "Vitreous haemorrhage ": 35.231536595786174} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/951.json new file mode 100644 index 00000000000..a5847f52a78 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/951.json @@ -0,0 +1 @@ +{"Confusional state ": 4.14339828602836, "Fall ": 13.921532541929569, "Hyponatraemia ": 16.34681190706136, "Inappropriate antidiuretic hormone secretion ": 127.0636169739774, "Mental status changes ": 45.407689271142, "Somnolence ": 5.116450159824217, "Wrist fracture ": 133.4719166609001} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/952.json new file mode 100644 index 00000000000..2d56d4bf14f --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/952.json @@ -0,0 +1 @@ +{"Agranulocytosis ": 10.16501930291214, "Anaphylactic reaction ": 2.9448325292803945, "Bronchospasm ": 7.977436285500203, "COVID-19 pneumonia ": 9.656751711134955, "Chest discomfort ": 2.315525257279948, "Cytokine release syndrome ": 5.886648882569596, "Dysphagia ": 3.24763391179389, "Dysphonia ": 3.551249212173429, "Dyspnoea ": 2.813128663126992, "Erythema ": 4.307301799748449, "Feeling hot ": 2.8585958553710897, "Flushing ": 5.677521770463573, "Hepatic cytolysis ": 9.220755875308834, "Hypersensitivity ": 2.846424826582385, "Hypotension ": 2.944731517168264, "Infusion related reaction ": 32.75428987528744, "Interstitial lung disease ": 2.103770410507968, "Laryngeal oedema ": 17.021341113537023, "Nasal congestion ": 4.475975245137927, "Neutropenia ": 3.7522762089759674, "Oropharyngeal discomfort ": 14.92179927166421, "Oxygen saturation decreased ": 10.308229891350392, "Pancytopenia ": 3.110215357561937, "Product use in unapproved indication ": 2.057349258444716, "Pruritus ": 4.361945542553429, "Rash ": 2.0491216448762763, "Rash maculo-papular ": 2.174883727483841, "Serum sickness ": 108.53942842560888, "Throat irritation ": 25.85324246592377, "Throat tightness ": 15.643042117437563, "Thrombocytopenia ": 2.3127552684957293, "Tumour lysis syndrome ": 15.228527141675633, "Urticaria ": 5.034284140491563} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/953.json new file mode 100644 index 00000000000..532fa010440 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/953.json @@ -0,0 +1 @@ +{"Abdominal abscess ": 9.802551288980698, "Abscess ": 12.76697828917951, "Abscess limb ": 16.375334716636576, "Acute respiratory failure ": 2.140948477912535, "Adenocarcinoma of colon ": 13.215535321994038, "Administration site erythema ": 4.555353574159624, "Administration site reaction ": 9.76559080280046, "Alanine aminotransferase increased ": 2.8387161044951994, "Alveolitis ": 6.007747942811758, "Anaphylactic reaction ": 2.1948980630238366, "Anaphylactoid reaction ": 2.5075888989323065, "Aneurysm ": 3.2738460299816365, "Aortic aneurysm ": 2.4132038316319524, "Aortic dissection ": 12.181739776967426, "Aphthous ulcer ": 6.506769765352767, "Appendicitis ": 3.035884836961405, "Arthritis ": 4.570244922257798, "Arthritis bacterial ": 52.76979609328048, "Arthritis infective ": 12.060393585170235, "Aspergillus infection ": 3.691255643890668, "Bacteraemia ": 2.070889258345577, "Bacterial sepsis ": 4.0289742310772665, "Basal cell carcinoma ": 6.237390607335793, "Blood bilirubin unconjugated increased ": 8.625370382212012, "Blood cholesterol increased ": 4.1322498031401205, "Blood fibrinogen decreased ": 28.473692933584942, "Blood triglycerides increased ": 3.868470873712615, "Breast cancer ": 2.355476740324448, "Bronchitis ": 2.9870738475352554, "Bursitis infective ": 45.55672976524258, "C-reactive protein decreased ": 20.935020794155918, "Cardiovascular insufficiency ": 9.13666196492407, "Cellulitis ": 6.728418253679414, "Cholecystitis ": 2.1185356113089937, "Cholecystitis acute ": 2.73903000671301, "Colectomy ": 4.268171263404194, "Complement factor C3 decreased ": 51.210197692023165, "Complement factor C4 decreased ": 68.89234096867287, "Conjunctivitis ": 2.706036538087259, "Cutaneous vasculitis ": 5.666156588459383, "Cyst ": 2.2720829103468296, "Cystitis ": 2.3483100403950345, "Demyelination ": 3.916072392354402, "Dermo-hypodermitis ": 46.81089203782034, "Device difficult to use ": 4.176812386467438, "Device related infection ": 8.41545010273417, "Diverticular perforation ": 123.6517494308418, "Diverticulitis ": 25.154669912635143, "Diverticulum ": 4.385108878102787, "Diverticulum intestinal ": 3.3951013805874832, "Drug delivery system malfunction ": 4.033659416823783, "Empyema ": 12.175701292448736, "Encephalitis ": 2.1181556979425618, "Encephalitis herpes ": 10.242279309257995, "Endocarditis ": 7.115966452420175, "Eosinophil count increased ": 2.203292143590022, "Eosinophilia ": 2.520556594026388, "Epiglottitis ": 18.876635679650526, "Erysipelas ": 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25.15007310612645, "Humerus fracture ": 4.200922381218249, "Hypercholesterolaemia ": 12.080394971391984, "Hypersensitivity ": 2.3153696596273066, "Hypertensive crisis ": 3.481496542311326, "Hypertransaminasaemia ": 3.7582705693042735, "Hypertriglyceridaemia ": 2.6715366198221475, "Hypofibrinogenaemia ": 84.09788450445117, "Ill-defined disorder ": 3.585409656612296, "Immunosuppression ": 3.630010803493457, "Impaired healing ": 2.662961609394065, "Infection ": 4.613048949273127, "Infectious pleural effusion ": 15.447790079377029, "Infusion related reaction ": 3.8298921110424806, "Injection site erythema ": 2.258374685064464, "Injection site haemorrhage ": 2.9192062701370878, "Injection site hypersensitivity ": 11.38466984580444, "Injection site oedema ": 4.684748817671361, "Injection site pruritus ": 2.566014453918702, "Injection site rash ": 8.080737646875523, "Injection site reaction ": 4.807364579615544, "Injection site urticaria ": 5.934573817635965, "Injury associated with device ": 6.305817697059696, "Intentional product use issue ": 10.91746812994703, "Intercepted product storage error ": 91.2333790269778, "Interleukin level increased ": 38.13758660722405, "Intermittent claudication ": 5.844934264630948, "International normalised ratio decreased ": 2.2931311523347, "Intervertebral discitis ": 23.955481382886827, "Intestinal haemorrhage ": 2.2840997311813798, "Intestinal ischaemia ": 3.0777713132913496, "Intestinal perforation ": 13.508199682716992, "Invasive ductal breast carcinoma ": 3.566458064282616, "Iritis ": 3.913541186695612, "Joint effusion ": 2.02321047590045, "Juvenile idiopathic arthritis ": 13.54834243078919, "Keratitis ": 4.899352643818668, "Large intestine perforation ": 23.01936606358383, "Leukopenia ": 7.27509717547501, "Lipids increased ": 14.949862124036123, "Liver abscess ": 8.002409543469943, "Liver function test increased ": 5.080413656551617, "Localised infection ": 4.935662320416527, "Loss of therapeutic response ": 24.85376139922004, "Low 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"Thyroid cancer ": 2.86594340249732, "Tonsillitis ": 2.988708181254945, "Tooth abscess ": 4.368585701232323, "Tooth disorder ": 2.76200650249902, "Transaminases increased ": 5.401867152349441, "Tuberculosis ": 5.4307525926416895, "Ulcerative keratitis ": 7.244791505876638, "Upper respiratory tract infection ": 3.0111873986057134, "Urinary tract infection ": 3.202303577403311, "Urosepsis ": 3.1017044890155963, "Urticaria ": 2.1563565363282, "Vasculitis ": 4.062132377885773, "Wound infection ": 4.691349370859911} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/954.json new file mode 100644 index 00000000000..9d3cd08f778 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/954.json @@ -0,0 +1 @@ +{"Acute myocardial infarction ": 10.607729548212124, "Arteriosclerosis ": 25.98107655929585, "Atrial fibrillation ": 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b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/955.json new file mode 100644 index 00000000000..787262c6173 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/955.json @@ -0,0 +1 @@ +{"Agitation ": 4.612722887600406, "Altered state of consciousness ": 8.57877698802745, "Crying ": 49.99577614566888, "Cyanosis ": 38.8852798724276, "Diarrhoea ": 3.822300686128263, "Febrile convulsion ": 94.908314252122, "Haematochezia ": 30.082022344830197, "Hypotonia ": 49.32683900561248, "Hypotonic-hyporesponsive episode ": 158.4509413574325, "Injection site erythema ": 4.666092149636292, "Injection site oedema ": 67.93583811313353, "Injection site warmth ": 5.178936562105896, "Intussusception ": 110.65632499809968, "Lethargy ": 5.092917150057466, "Pallor ": 31.68844573933464, "Rotavirus infection ": 278.5709048829182, "Seizure ": 4.156488645428448, "Somnolence ": 2.363075003142224, "Unresponsive to stimuli ": 19.37607921844701, "Vomiting ": 3.4204404361414475} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/956.json new file mode 100644 index 00000000000..2f1b37b05d2 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/956.json @@ -0,0 +1 @@ +{"Autism spectrum disorder ": 218.14145827741063, "Dehydration ": 10.289193891678735, "Diarrhoea ": 2.6816781958229385, "Gastroenteritis ": 134.8481763047518, "Intestinal obstruction ": 551.3179136022165, "Intussusception ": 607.3828774637363, "Language disorder ": 167.08595571253818, "Metal poisoning ": 1116.1260303304462, "Neurological symptom ": 123.43464368199488, "Pyrexia ": 2.348532485624861, "Vomiting ": 2.4963923697950223} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/957.json 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"Pallor ": 10.1835103315336, "Petechiae ": 2.2613576401587507, "Pharyngeal erythema ": 13.229747586236387, "Poor feeding infant ": 18.78964523807031, "Poor quality sleep ": 2.753218166522784, "Product administered to patient of inappropriate age ": 21.06347028043164, "Rectal haemorrhage ": 2.403234445151947, "Regurgitation ": 47.10181395724627, "Respiratory syncytial virus infection ": 5.095594102355359, "Restlessness ": 6.300689708218667, "Retching ": 2.35156960741533, "Rhinitis ": 3.664601465994487, "Rotavirus infection ": 1864.961970002797, "Rotavirus test positive ": 10751.495924523562, "Salmonellosis ": 21.529745053860704, "Screaming ": 30.956921983246534, "Secondary transmission ": 137.78317015243871, "Selective eating disorder ": 16.760705427012635, "Small intestinal obstruction ": 3.438239630486306, "Sudden infant death syndrome ": 45.34884902881807, "Surgery ": 9.262282280071972, "Tearfulness ": 4.29196254850502, "Thrombocytopenic purpura ": 34.92222192097596, "Tooth 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a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/959.json new file mode 100644 index 00000000000..71faa8cb41e --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/959.json @@ -0,0 +1 @@ +{"Accidental underdose ": 15.58824161343866, "Acute myeloid leukaemia ": 2.0236207879988832, "Adverse drug reaction ": 2.6676802329273364, "Adverse event ": 27.40599369339656, "Alanine aminotransferase increased ": 5.712813801765201, "Anaemia ": 6.530667060772686, "Ascites ": 4.4295438950554695, "Aspartate aminotransferase increased ": 4.882063655985347, "Asthenia ": 2.229463512257189, "Blood alkaline phosphatase increased ": 2.566268309356594, "Blood creatinine increased ": 7.525438598676626, "Blood magnesium decreased ": 33.12169306081485, "Blood potassium decreased ": 5.754090876297713, "Blood sodium decreased ": 2.591703245579112, "Blood test abnormal ": 8.182961645812316, "Carbohydrate antigen 125 increased ": 822.8072402865545, "Constipation ": 5.132886110970955, "Cytopenia ": 2.256026468290968, "Death ": 3.946058961384429, "Decreased appetite ": 3.0903596724900027, "Dehydration ": 5.043125168538401, "Drug intolerance ": 2.3966967651935382, "Dysgeusia ": 8.58117751879402, "Full blood count abnormal ": 11.69700743732657, "Glomerular filtration rate decreased ": 4.193727772477089, "Haematocrit decreased ": 5.8683464905226925, "Haematotoxicity ": 4.10209729463261, "Haemoglobin decreased ": 8.746314146323266, "Hernia ": 6.633738957093603, "Hypersomnia ": 2.5809900352431043, "Hypertransaminasaemia ": 5.010802015573565, "Hypophagia ": 11.623187792810995, "Illness ": 2.1399406483950565, "Intentional underdose ": 12.42558380467375, "Intestinal obstruction ": 15.398804757094736, "Laboratory test abnormal ": 14.57198169930636, "Liver function test abnormal ": 3.320690882441154, "Liver function test increased ": 6.4920965469468825, "Malignant 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"Sunburn ": 13.300510090289832, "Surgery ": 4.27672475825635, "Taste disorder ": 5.807960413659807, "Therapy partial responder ": 15.494220586701829, "Thrombocytopenia ": 4.231605740596249, "Transaminases increased ": 2.0770075614156966, "Transfusion ": 9.138928960232992, "Tumour marker increased ": 27.72934008417512, "Underdose ": 11.124479474940012, "Urinary tract infection ": 2.239860888398015, "Vomiting ": 2.1140566544432366, "White blood cell count decreased ": 4.619791886356677} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/96.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/96.json new file mode 100644 index 00000000000..25a4f530d9f --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/96.json @@ -0,0 +1 @@ +{"Blister ": 50.60769786611604, "Conjunctivitis ": 236.7319672946979, "Genital erosion ": 7210.221152950711, "Lip erosion ": 2995.653479617848, 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file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/962.json new file mode 100644 index 00000000000..ebe19088e60 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/962.json @@ -0,0 +1 @@ +{"Drug ineffective ": 6.815424653327351, "Off label use ": 7.967177607368685, "Product use issue ": 25.461701209919077, "Seizure ": 15.031197376624112, "Therapy non-responder ": 34.21516320776984, "Treatment failure ": 110.27445421657272} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/963.json new file mode 100644 index 00000000000..6ef4fec2e27 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/963.json @@ -0,0 +1 @@ +{"Off label use ": 6.394765689587745} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/964.json new file mode 100644 index 00000000000..554264a785d --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/964.json @@ -0,0 +1 @@ +{"Acute graft versus host disease ": 10.048406242167546, "Acute myeloid leukaemia ": 16.14233706205119, "Anaemia ": 10.02495019478464, "BK virus infection ": 23.62533352555422, "Basal cell carcinoma ": 15.14115750571396, "Basophil count increased ": 93.88774821125796, "Blood lactate dehydrogenase increased ": 5.94750162090218, "Bronchopulmonary aspergillosis ": 12.569243110210758, "Chronic graft versus host disease ": 29.79428541269381, "Concomitant disease aggravated ": 10.24179554525715, "Cytomegalovirus infection ": 15.936931540109356, "Cytomegalovirus infection reactivation ": 27.362096545156287, "Cytopenia ": 25.42609783087823, "Disease 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a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/97.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/97.json new file mode 100644 index 00000000000..682a22b5359 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/97.json @@ -0,0 +1 @@ +{"Hormone-refractory prostate cancer ": 357.33944216139383, "Malignant neoplasm progression ": 5.112240598587916, "Prostate cancer metastatic ": 383.29016688632737, "Prostatic specific antigen increased ": 97.51335005611386, "Rash ": 5.321744298382776} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/970.json new file mode 100644 index 00000000000..0100dea7f2e --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/970.json @@ -0,0 +1 @@ +{"Blood lactic acid increased ": 300.6426071405326, "Diplopia 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b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/972.json @@ -0,0 +1 @@ +{"Acute kidney injury ": 4.392615441494683, "Bradycardia ": 11.208902794701231, "Hyperkalaemia ": 18.62037132838603, "Hypoglycaemia ": 13.641553716214377, "Hypotension ": 5.807094665640416} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/973.json new file mode 100644 index 00000000000..c6680e13ee6 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/973.json @@ -0,0 +1 @@ +{"Abdominal distension ": 5.957598101981265, "Abdominal pain ": 3.4936723303290007, "Abdominal pain upper ": 3.821252996149209, "Abortion ": 5.70146086621288, "Abortion spontaneous ": 2.41651665995451, "Amylase increased ": 7.238104714883996, "Appendicitis ": 3.4932959877051197, "Appetite disorder ": 24.66198093097622, "Autoimmune thyroiditis ": 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a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/974.json new file mode 100644 index 00000000000..73739824f09 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/974.json @@ -0,0 +1 @@ +{"Cardiac failure ": 4.535799713528884, "Disease progression ": 4.406367710131015, "Electrocardiogram QT prolonged ": 10.286915074612551, "Lipase increased ": 47.84433307375701, "Neutropenia ": 3.896416019654568, "Off label use ": 2.014428392097531, "Pancreatitis ": 11.790948559960835, "Pancytopenia ": 10.519882618710938, "Platelet count decreased ": 8.565671453799533, "Thrombocytopenia ": 13.530184539929612, "White blood cell count decreased ": 3.248883719516391} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/975.json new file mode 100644 index 00000000000..7a27c364dd3 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/975.json @@ -0,0 +1 @@ +{"Anxiety ": 2.7059062670482086, "Asthma ": 14.51042168383211, "Chest discomfort ": 7.563712124875466, "Chronic obstructive pulmonary disease ": 11.00004518009037, "Cough ": 4.198131622987876, "Cyanosis ": 17.006274048108452, "Depression ": 2.6814969961020743, "Dyspnoea ": 2.839411147836903, "Dyspnoea exertional ": 14.482065994242468, "Emphysema ": 44.10726862854626, "Fall ": 2.58830327345888, "Gait disturbance ": 2.6081291657201287, "Hiatus hernia ": 39.99138034595639, "Hypoaesthesia ": 3.45494405934379, "Infection ": 5.994181775268377, "Insomnia ": 2.8428971111175256, "Overdose ": 5.28533097805287, "Pneumonia ": 4.802134285370815, "Wheezing ": 8.824417980937305} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/976.json new file mode 100644 index 00000000000..b150e86fcf7 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/976.json @@ -0,0 +1 @@ +{"Abdominal pain ": 2.452993672888997, "Agitation ": 17.25798036615297, "Contraindicated product administered ": 43.16914042468668, "Drug interaction ": 11.202118021478356, "Drug withdrawal syndrome ": 169.31686542854504, "Hyperhidrosis ": 3.3945568991737725, "Tremor ": 5.122760114248426, "Vomiting ": 2.338238382155612, "Withdrawal syndrome ": 146.44392034752178} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/977.json new file mode 100644 index 00000000000..3e65fd99c41 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/977.json @@ -0,0 +1 @@ +{"Abdominal distension ": 3.803648615338737, "Abnormal dreams ": 13.85767641076035, "Alanine aminotransferase increased ": 3.23207518169336, "Aspartate aminotransferase increased ": 3.69442241785508, "Blood creatine phosphokinase increased ": 5.964969262642309, "Blood iron decreased ": 53.70211449605184, "Cardiac failure congestive ": 3.321421416109072, "Dyspepsia ": 4.174230861818576, "Feeling abnormal ": 3.0819472255478364, "Fluid retention ": 10.271647889462724, "Hyperhidrosis ": 8.677378671384481, "Hypoglycaemia ": 2.0805126115547115, "Hypotension ": 2.5863873547714142, "Loss of consciousness ": 13.864678498138977, "Malaise ": 2.942363592521839, "Muscle spasms ": 13.696256817795092, "Myalgia ": 2.0151036703337253, "Nasopharyngitis ": 3.130926206794654, "Pain in extremity ": 3.958832904283301, "SARS-CoV-2 test positive ": 12.460136442818133, "Sleep disorder ": 23.535549495256504, "Weight decreased ": 2.913650581537416, "Wrong technique in product usage process ": 4.325201595762777} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/978.json new file mode 100644 index 00000000000..63333ecd2e4 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/978.json @@ -0,0 +1 @@ +{"Blood glucose increased ": 10.244760568773994, "Device defective ": 367.6225842969492, "Device issue ": 208.83513639037133, "Device mechanical issue ": 3579.844043190258, "Lipodystrophy acquired ": 373.8506342293514} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/979.json new file mode 100644 index 00000000000..19014a8861f --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/979.json @@ -0,0 +1 @@ +{"Anxiety ": 4.85346854084976, "Completed suicide ": 14.871168272252872, "Craniocerebral injury ": 167.3458246406038, "Depression ": 8.940130051093895, "Disturbance in attention ": 5.686928432736939, "Drug ineffective ": 2.160587792198032, "Drug interaction ": 7.201249448703478, "Fall ": 4.886163105432081, "Mental disorder ": 14.850121211582309, "Overdose ": 2.7941216912224616, "Somnolence ": 5.187009858581808, "Suicidal ideation ": 4.669139802160048, "Tension ": 111.91417830769328} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/98.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/98.json new file mode 100644 index 00000000000..c68f73da44c --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/98.json @@ -0,0 +1 @@ +{"Pyrexia ": 2.457279491154506} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/980.json new file mode 100644 index 00000000000..5a51ee609f6 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/980.json @@ -0,0 +1 @@ +{"Acute disseminated encephalomyelitis ": 4.933298989315599, "Adverse reaction ": 2.345142765917581, "Allodynia ": 5.414745025642478, "Areflexia ": 2.481457877917973, "Bedridden ": 7.999370464617441, "Bell's palsy ": 6.537760825699066, "Blister ": 8.610809653613563, "Burning sensation ": 3.4613820752133324, "Cataract nuclear ": 10.838850829974946, "Cellulitis ": 4.505923853931332, "Coronavirus infection ": 3.585258967277259, "Deafness unilateral ": 2.586832722419568, "Demyelinating polyneuropathy ": 5.473951036233877, "Demyelination ": 2.744088513231518, "Diplegia ": 2.131450858535953, "Disease prodromal stage ": 165.76668080753683, "Dysaesthesia ": 2.8905713208285144, "Encephalitis ": 3.3898367066919715, "Encephalitis viral ": 4.673784061810857, "Erysipelas ": 2.025042717552456, "Erythema ": 3.932258186552604, "Erythema of eyelid ": 2.3120989233592377, "Extensive swelling of vaccinated limb ": 2.789259949399849, "Extra dose administered ": 5.62001279064319, "Eyelid function disorder ": 6.768377804158275, "Facial pain ": 4.525290989994191, "Facial paralysis ": 2.898783531907706, "Facial paresis ": 2.7140209439453, "Genital herpes ": 4.082154682408016, "Genital herpes zoster ": 24.78772370011829, "Genital rash ": 5.188881946145443, "Giant cell arteritis ": 2.9806985227915392, "Groin pain ": 2.608380318746482, "Guillain-Barre syndrome ": 13.135795378956232, "Herpes ophthalmic ": 17.45890440622003, "Herpes simplex ": 8.856628670201761, "Herpes virus infection ": 7.40865426325525, "Herpes zoster ": 40.42503127967853, "Herpes zoster cutaneous disseminated ": 36.22663769366602, "Herpes zoster disseminated ": 10.525816003714905, "Herpes zoster oticus ": 32.34507630398697, "Herpes zoster reactivation ": 26.978841374842805, "Hordeolum ": 3.615883212957467, "Hyperaesthesia ": 10.07633204483132, "Immobile ": 4.709129800598367, "Inappropriate schedule of product administration ": 2.5767991977469977, "Incomplete course of vaccination ": 109.4928881444932, "Incorrect route of product administration ": 4.319765846356616, "Induration ": 6.626357417620879, "Influenza like illness ": 2.436974412323524, "Injected limb mobility decreased ": 10.441437278510396, "Injection site cellulitis ": 6.530320765352262, "Injection site discolouration ": 5.046640069872426, "Injection site discomfort ": 2.602954285544476, "Injection site erythema ": 5.500099841118324, "Injection site induration ": 2.732815818348413, "Injection site pain ": 2.418107481043463, "Injection site paraesthesia ": 3.400698010385687, "Injection site pruritus ": 2.199849579983649, "Injection site rash ": 5.68896327002099, "Injection site swelling ": 3.569833087863631, "Injection site urticaria ": 2.1352605955515496, "Injection site vesicles ": 16.17702748093092, "Injection site warmth ": 2.3752134852848696, "Keratitis ": 2.306277065812683, "Lip blister ": 6.88812791092473, "Local reaction ": 18.19812847694293, "Loss of personal independence in daily activities ": 2.4680461370999, "Lyme disease ": 3.075687566700229, "Lymphangitis ": 4.846824258841722, "Mobility decreased ": 3.374531468335576, "Monoplegia ": 3.3504338913242737, "Myelitis transverse ": 3.615304624341296, "Near death experience ": 2.390199920178497, "Neck pain ": 2.0036743922054576, "Nerve injury ": 3.661290444507724, "Neuralgia ": 10.176061067158184, "Neuralgic amyotrophy ": 5.856573990103475, "Neuritis ": 4.008085739666925, "Nuchal rigidity ": 2.106848332491285, "Occipital neuralgia ": 6.811069586264487, "Ophthalmic herpes simplex ": 24.165679154344176, "Ophthalmic herpes zoster ": 40.93649928081029, "Oral herpes ": 9.725664672497496, "Oral mucosal blistering ": 3.5862812780054707, "Pain ": 3.0336105842129872, "Pain in extremity ": 3.0119131796131686, "Pain of skin ": 7.593015475575824, "Paralysis ": 2.8871048689421164, "Paresis ": 2.0918397076855904, "Peripheral swelling ": 2.3111403842813765, "Peripheral vascular disorder ": 3.63445877473144, "Photophobia ": 2.156099987719906, "Polymyalgia rheumatica ": 5.157116798092937, "Post herpetic neuralgia ": 44.72816960934562, "Product administered at inappropriate site ": 6.27996401683862, "Product administered to patient of inappropriate age ": 19.92911847991682, "Product supply issue ": 9.317305533237832, "Pruritus ": 2.4041225153954917, "Pustule ": 6.682751848251535, "Rash ": 2.785161541227747, "Rash erythematous ": 2.058244239464839, "Rash macular ": 2.0877453918095847, "Rash papular ": 2.750786067681384, "Rash pruritic ": 2.646759493432042, "Rash pustular ": 5.398692419341064, "Rash vesicular ": 37.92686597504371, "Scab ": 5.896810379119218, "Scar ": 4.1891411260517, "Sensitive skin ": 2.130809912542475, "Skin irritation ": 2.087154532336783, "Skin lesion ": 3.7751905352692336, "Skin warm ": 7.371041915438083, "Social problem ": 2.6676622469391456, "Swelling ": 2.4234070669453565, "Tenderness ": 2.323960855289271, "Trigeminal neuralgia ": 4.371691530872508, "Vaccination failure ": 7.83525686928528, "Vaccination site erythema ": 3.121030838091634, "Vaccination site induration ": 2.660334521140563, "Vaccination site inflammation ": 5.729856469302089, "Vaccination site joint swelling ": 4.963823471425084, "Vaccination site oedema ": 2.3788726115111585, "Vaccination site rash ": 2.357277570363777, "Vaccination site reaction ": 2.465968547612385, "Vaccination site swelling ": 2.5347762362199484, "Vaccination site warmth ": 3.654581646572177, "Varicella ": 2.381712401955125, "Varicella zoster virus infection ": 10.863486284427804, "Vestibular neuronitis ": 2.025822824028672, "Walking aid user ": 2.5429212659521205} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/981.json new file mode 100644 index 00000000000..398582c1234 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/981.json @@ -0,0 +1 @@ +{"Abnormal behaviour ": 5.513847270309444, "Abnormal dreams ": 4.549356890943895, "Aggression ": 5.269033713701167, "Agitation ": 5.282561823073042, "Apathy ": 2.982740107341061, "Behaviour disorder ": 16.669319252473922, "Bipolar disorder ": 14.717135730229309, "Blood creatine phosphokinase increased ": 2.2590907344583733, "Bulimia nervosa ": 236.9393873635864, "Chromaturia ": 2.81198359050999, "Circulatory collapse ": 2.080122945048522, "Cognitive disorder ": 3.0722213782506933, "Compulsive sexual behaviour ": 242.80041011613463, "Compulsive shopping ": 722.4348656547571, "Condition aggravated ": 2.0629572914169625, "Confusional state ": 3.8568550732206095, "Delirium ": 6.279004804662711, "Delusion ": 5.636504886584267, "Dementia ": 3.323804362684906, "Dependence ": 19.03212372873904, "Depression ": 2.206091542051284, "Diplopia ": 4.799839783460544, "Dyskinesia ": 12.306324604090507, "Dystonia ": 5.454671926522068, "Eating disorder ": 6.481126856873063, "Economic problem ": 2.3264920782076506, "Emotional disorder ": 4.114688556790301, "Fall ": 2.589194973438706, "Fear ": 3.7696767035812018, "Food craving ": 28.259577915258152, "Gait disturbance ": 2.173291515652892, "Gambling ": 231.20483300422177, "Gambling disorder ": 821.3678350455043, "Hallucination ": 17.357361828954794, "Hallucination, auditory ": 6.003134274361014, "Hallucination, visual ": 27.067351593524997, "Hepatic steatosis ": 2.793041950447652, "Hyperkinesia ": 57.17855982258489, "Hyperphagia ": 20.000566725393885, "Hypersexuality ": 348.30223798376875, "Impulse-control disorder ": 477.8563340275925, "Insomnia ": 2.737387988726551, "Intestinal obstruction ": 3.372427046127813, "Libido increased ": 68.8112909051405, "Mania ": 5.120873990572349, "Medication error ": 2.637235467890542, "Mental disorder ": 4.908716868074454, "Mental impairment ": 3.1143873074312083, "Motor dysfunction ": 4.883028722099444, "Muscle rigidity ": 4.681903116351543, "Nightmare ": 3.913379328905386, "Nikolsky's sign ": 64.05248677783362, "Obsessive-compulsive disorder ": 20.97054602236829, "Oedema peripheral ": 5.378747567457739, "On and off phenomenon ": 71.00047408638419, "Orthostatic hypotension ": 5.726944059099861, "Overdose ": 2.5762404735889946, "Panic attack ": 2.224470168023422, "Paranoia ": 4.578169682881997, "Parkinson's disease ": 15.664549898185424, "Parkinsonism ": 12.737749659104246, "Personality change ": 11.775302922678398, "Product residue present ": 8.836813178268656, "Psychomotor hyperactivity ": 17.707000380016478, "Psychotic disorder ": 4.195641263478115, "Rash papular ": 3.7677820191499465, "Restless legs syndrome ": 28.826429076411973, "Restlessness ": 3.6987992323590873, "Rhabdomyolysis ": 2.720041660178831, "Road traffic accident ": 4.237886059468402, "Sleep attacks ": 148.7369415378984, "Sleep disorder ": 5.621318224776958, "Somnolence ": 4.6624266050746455, "Stereotypy ": 174.20719820759956, "Stevens-Johnson syndrome ": 2.3956492362203927, "Sudden onset of sleep ": 105.48880376705112, "Suicide attempt ": 6.288174730926103, "Therapeutic product effect decreased ": 3.0787677808053973, "Toxic epidermal necrolysis ": 3.383928282951689, "Tremor ": 2.465815858571809, "Urinary hesitation ": 21.89736590855564, "Weight increased ": 2.83760571523999, "Withdrawal syndrome ": 4.069195062798588} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/982.json new file mode 100644 index 00000000000..7cbc33500d8 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/982.json @@ -0,0 +1 @@ +{"Blood glucose increased ": 6.740362856729726, "Diabetes mellitus ": 29.916075994128832, "Diarrhoea ": 2.9543420369916387, "Electrocardiogram QT prolonged ": 7.4799445025262035, "Glycosylated haemoglobin increased ": 27.43364251437124, "Hyperglycaemia ": 46.301680078031445, "Product use in unapproved indication ": 3.3022063131151542, "Weight decreased ": 2.9265723616837835} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/983.json new file mode 100644 index 00000000000..9400fb2339c --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/983.json @@ -0,0 +1 @@ +{"Acute myocardial infarction ": 5.27425411888543, "Acute respiratory failure ": 2.0849890719467794, "Aortic valve stenosis ": 18.686773899753693, "Ascites ": 2.159338827572346, "Blindness ": 2.77538486915733, "Blindness unilateral ": 2.292071863349082, "Blood potassium decreased ": 3.849831335416373, "Blood pressure abnormal ": 2.812260876014433, "Blood pressure decreased ": 3.196709479030938, "Blood pressure diastolic abnormal ": 17.986525269218156, "Blood pressure diastolic increased ": 8.626600819360837, "Blood pressure systolic abnormal ": 18.298201427140228, "Blood pressure systolic increased ": 2.83232864221768, "Blood urine present ": 2.154138867592138, "Bradycardia ": 3.032438785622027, "Cardiac arrest ": 3.117569094702355, "Cardiac failure ": 3.3668424705518327, "Cardiac failure chronic ": 6.243108876084706, "Cardio-respiratory arrest ": 2.598528224645253, "Cardiogenic shock ": 5.457572158318087, "Cardiomegaly ": 3.838548750865446, "Cardioversion ": 16.144124748598774, "Carotid artery stenosis ": 8.654882544316697, "Circulatory collapse ": 2.361503825826227, "Completed suicide ": 3.952708396662169, "Disease progression ": 2.1215191073545943, "Drug ineffective for unapproved indication ": 2.036832974608958, "Drug interaction ": 2.922029830485636, "Dyschromatopsia ": 23.04524250915977, "Dyspepsia ": 3.1599159678592583, "Dyspnoea exertional ": 4.203366135241993, "Ear infection ": 2.7089588197975654, "Emotional disorder ": 2.3232156438278952, "Erectile dysfunction ": 7.753459628164362, "Erection increased ": 13.849516792828432, "Essential hypertension ": 10.512962713762334, "Exercise tolerance decreased ": 2.0939113016873887, "Eye haemorrhage ": 3.340113090596747, "Fluid retention ": 5.228181747611984, "Flushing ": 5.172087673620214, "Foetal exposure during pregnancy ": 3.8869326701876297, "Foetal growth restriction ": 5.807199561487288, "Haemodynamic instability ": 13.95609906640038, "Haemoperitoneum ": 11.033157092236992, "Haemoptysis ": 3.241616977688742, "Hypervolaemia ": 8.36017983770305, "Hypoacusis ": 2.927163252978739, "Hypotension ": 4.003674522018887, "Hypoxia ": 4.075372613822369, "Implantable defibrillator insertion ": 25.749770746545995, "Intentional product misuse ": 2.088038196609052, "Ischaemic stroke ": 3.8034227662386986, "Left 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a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/985.json new file mode 100644 index 00000000000..b2b1f7a5c4c --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/985.json @@ -0,0 +1 @@ +{"Acute kidney injury ": 2.272005504017268, "Aspartate aminotransferase increased ": 5.423597768572754, "Drug interaction ": 3.230265018571265, "Ejaculation disorder ": 429.8428525703207, "Ejaculation failure ": 286.1101086178015, "Hepatic function abnormal ": 8.72391390976674, "Loss of consciousness ": 8.387300798338616, "Orthostatic hypotension ": 29.59600039660548, "Prostate cancer ": 37.36992534930331, "Retrograde ejaculation ": 777.6218048306735, "Syncope ": 6.065066819576177, "Urinary retention ": 10.201231061991292} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/986.json new file mode 100644 index 00000000000..954b4248c7e --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/986.json @@ -0,0 +1 @@ +{"Dizziness ": 2.793465152464892, "Ejaculation disorder ": 137.4318489637387, "Ejaculation failure ": 726.424772227731, "Erectile dysfunction ": 35.6252305452816, "Fall ": 2.411651125548482, "Hypotension ": 2.4335698850660203, "Nasal congestion ": 27.12149106958791, "Orthostatic hypotension ": 25.114345544340733, "Pollakiuria ": 14.650789830120049, "Retrograde ejaculation ": 2112.8729472760488, "Syncope ": 2.8974743140765757} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/987.json new file mode 100644 index 00000000000..b5cb4e52e64 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/987.json @@ -0,0 +1 @@ +{"Alanine aminotransferase increased ": 2.885063112311953, "Ascites ": 7.538686831364737, "Aspartate aminotransferase increased ": 2.9123573867681998, "Blood bilirubin increased ": 14.569413886960778, "Blood creatinine increased ": 3.510474653105271, "Death ": 2.070935707180888, "Drug hypersensitivity ": 2.618375889150215, "Drug ineffective ": 8.257394206336315, "Drug interaction ": 6.683616115460725, "Hepatic failure ": 7.729320461372979, "Hepatic function abnormal ": 2.908375892489848, "Hepatitis B reactivation ": 51.36221335161509, "Hepatitis C ": 234.90436308015376, "Hyperbilirubinaemia ": 37.07307716573468, "Jaundice ": 6.590644487737361, "Off label use ": 11.207440750257168, "Pancreatitis acute ": 7.570739143679191, "Photosensitivity reaction ": 23.011967925880302, "Product use issue ": 14.839077771030553, "Remission not achieved ": 615.722476591015, "Sinus bradycardia ": 25.700989384498843, "Treatment failure ": 20.24657257766281} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/988.json new file mode 100644 index 00000000000..16e4716aa5e --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/988.json @@ -0,0 +1 @@ +{"Abdominal abscess ": 2.7112756746622257, "Abnormal loss of weight ": 2.036153686104346, "Abscess ": 6.352695421455475, "Abscess limb ": 6.587175574871973, "Abscess oral ": 8.94645775188156, "Accident ": 3.2820869986107435, "Accidental exposure to product ": 35.56048966732856, "Accidental underdose ": 3.5629666945834844, "Adenocarcinoma of colon ": 4.228186817157243, "Administration site bruise ": 12.788536084676805, "Administration site infection ": 394.952495009093, "Adverse drug reaction ": 2.106367527193627, "Adverse event ": 2.8201674592908885, "Alopecia areata 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9.3386349855681, "Incorrect dose administered ": 3.3989102635379957, "Infected skin ulcer ": 11.389845601479012, "Infection ": 8.20750251453754, "Infectious mononucleosis ": 2.3080218059244104, "Infectious pleural effusion ": 7.1526169819697145, "Inflammation ": 2.1807749665547336, "Inflammatory bowel disease ": 2.4327272292744544, "Influenza ": 3.658129551757393, "Ingrowing nail ": 4.876522769649607, "Injection related reaction ": 2.143739096956063, "Injection site bruising ": 3.449766689459083, "Injection site extravasation ": 2.0683739426887, "Injection site haemorrhage ": 12.93160701166396, "Injection site hypoaesthesia ": 2.6203940550544287, "Injury associated with device ": 21.941792102594867, "Intervertebral disc operation ": 14.72022707437045, "Intervertebral disc protrusion ": 4.112048057089912, "Intestinal operation ": 22.16145748536113, "Intestinal resection ": 3.927637104681093, "Intraductal proliferative breast lesion ": 4.660898297822259, "Invasive ductal breast carcinoma ": 2.896643699582359, "Iridocyclitis ": 4.692585693953031, "Iritis ": 3.844948164872117, "Joint arthroplasty ": 15.044982719827551, "Joint dislocation ": 2.961737509164242, "Joint effusion ": 2.78675618818426, "Joint lock ": 3.547812834321786, "Joint surgery ": 22.57062903151303, "Joint swelling ": 2.242319374163817, "Juvenile idiopathic arthritis ": 5.119132332524507, "Kidney infection ": 5.884316091920942, "Knee arthroplasty ": 11.68139631167842, "Knee operation ": 18.93369338510496, "Labyrinthitis ": 3.1570523568812368, "Laryngitis ": 2.31615460552948, "Latent tuberculosis ": 9.905819472136274, "Ligament rupture ": 2.7655278369001755, "Ligament sprain ": 2.2760218882182754, "Limb mass ": 7.881293011568928, "Limb operation ": 23.25870233215681, "Localised infection ": 7.508136202735399, "Loss of therapeutic response ": 19.745426658500097, "Lower limb fracture ": 3.4999703139694964, "Lower respiratory tract infection ": 31.340362958976165, "Lung adenocarcinoma ": 6.318837031042986, "Lung neoplasm malignant ": 2.170709280523144, "Lupus nephritis ": 7.734788400795993, "Lupus-like syndrome ": 12.78058568188752, "Lyme disease ": 2.1293046444539776, "Lymph node tuberculosis ": 19.511815467239437, "Lymphocytosis ": 3.1898214192986534, "Lymphoma ": 4.334434223123927, "Lymphoproliferative disorder ": 5.8974497851605765, "Malignant melanoma ": 4.127388079783122, "Marasmus ": 7.252200203772163, "Mass ": 2.8254636166684803, "Medical device implantation ": 12.894906770410708, "Melanocytic naevus ": 5.80786831435327, "Meniscus injury ": 3.197942813221633, "Metabolic surgery ": 9.661356747326696, "Mucous stools ": 3.0455893958702296, "Multiple sclerosis ": 4.120764921466942, "Mycobacterium tuberculosis complex test positive ": 17.61127486185552, "Myelitis ": 2.9197213969571445, "Nasopharyngitis ": 6.057701915236309, "Neck mass ": 3.1235783360129656, "Neck surgery ": 6.978428468167049, "Needle issue ": 30.787679840954063, "Neoplasm ": 4.087961818509343, "Neoplasm malignant ": 2.251512043305429, "Nephrolithiasis ": 2.5735826667052235, "Nerve compression ": 2.410458561107661, "Off label use ": 3.410387744116109, "Optic neuritis ": 2.936252398692796, "Oral fungal infection ": 2.3414551151931, "Oral herpes ": 3.464327395712661, "Oral infection ": 7.165432470939846, "Organising pneumonia ": 3.6307687913081903, "Osteitis ": 5.141914925284588, "Osteoarthritis ": 2.9188609494900883, "Osteomyelitis ": 5.52061225692662, "Ovarian cancer ": 2.204509909589928, "Ovarian cyst ": 2.248867030538873, "Palmoplantar pustulosis ": 43.74717196032708, "Papillary thyroid cancer ": 4.140200018149041, "Papilloma viral infection ": 4.7816475224493775, "Paradoxical drug reaction ": 4.528254006373663, "Paternal exposure during pregnancy ": 13.403767429590582, "Periodontitis ": 3.2935843976316392, "Peritoneal tuberculosis ": 41.63369215343048, "Pharyngitis ": 13.136003645350218, "Pleurisy ": 3.828720880812159, "Pneumocystis jirovecii pneumonia ": 7.1081865439948215, "Pneumonia ": 3.399901393480308, "Pneumonia bacterial ": 5.376148546687255, "Pneumonia legionella ": 8.583554706470188, "Polyarthritis ": 2.793992191043352, "Poor quality product administered ": 6.066648723042844, "Post procedural complication ": 2.14598878252412, "Post procedural infection ": 12.204378354764938, "Postoperative wound infection ": 3.95207084057368, "Product availability issue ": 3.240605375659636, "Product dose omission issue ": 26.76571544098468, "Product label issue ": 5.478927097540825, "Product leakage ": 4.412322200448869, "Product packaging issue ": 5.042618412150207, "Product packaging quantity issue ": 5.663599511864924, "Product quality issue ": 3.685320170090673, "Product storage error ": 10.434149359929174, "Product temperature excursion issue ": 15.615022045150988, "Product use issue ": 4.083128065649463, "Prostate cancer ": 2.0653169739433515, "Psoriasis ": 8.804527773910243, "Psoriatic arthropathy ": 16.789623502663087, "Pulmonary sarcoidosis ": 8.979997762353072, "Pulmonary tuberculosis ": 20.26155849850413, "Pustular psoriasis ": 17.75636317132952, "Pyelonephritis ": 4.778816399039005, "Pyelonephritis acute ": 2.8273420175051323, "Pyoderma gangrenosum ": 6.170425806881032, "Rectal cancer ": 3.151996934427093, "Red blood cell sedimentation rate increased ": 2.2641024436007475, "Respiratory tract infection ": 4.77211241465386, "Respiratory tract infection viral ": 4.627088503696209, "Rheumatic disorder ": 5.415924955997225, "Rheumatoid arthritis ": 11.598284237768317, "Rheumatoid factor increased ": 11.118534032085968, "Rheumatoid vasculitis ": 69.44604739646384, "Rhinitis ": 2.637103055920506, "Sacroiliitis ": 4.213360950886609, "Sarcoidosis ": 5.997387746254527, "Scleritis ": 7.208102999170163, "Seasonal allergy ": 2.26122216087789, "Sepsis ": 2.069441839997049, "Serum ferritin decreased ": 3.480895365711731, "Shoulder arthroplasty ": 7.881198650214441, "Shoulder operation ": 14.517138607867851, "Sinusitis ": 3.250511931828776, "Sjogren's 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25.204321894204767, "Wound complication ": 4.269209330935535, "Wound infection ": 2.473830686870849, "Wrist surgery ": 13.54534382099552} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/989.json new file mode 100644 index 00000000000..5569b8bc4ec --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/989.json @@ -0,0 +1 @@ +{"Blood creatinine increased ": 10.554728842142492, "Kidney transplant rejection ": 453.1409148085539} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/99.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/99.json new file mode 100644 index 00000000000..d5cd5aa7e09 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/99.json @@ -0,0 +1 @@ +{"Accidental overdose ": 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4.3416142873570704, "Cold sweat ": 6.389651502926942, "Coronary artery bypass ": 2.067180869317517, "Cystoid macular oedema ": 18.28054947007877, "Decreased insulin requirement ": 86.5598897231919, "Dengue fever ": 7.023262360475538, "Device breakage ": 10.872104828391423, "Device defective ": 10.500894062131238, "Device delivery system issue ": 10.14842775513015, "Device failure ": 2.672783589001094, "Device issue ": 25.297186875418888, "Device leakage ": 6.973198821459808, "Device malfunction ": 5.668482407997738, "Device operational issue ": 149.2685631211664, "Device use issue ": 9.380587072768376, "Diabetes mellitus inadequate control ": 35.97878951050089, "Diabetic coma ": 16.647019762471544, "Diabetic hyperglycaemic coma ": 14.604165075366192, "Diabetic ketoacidosis ": 10.414905369798202, "Diabetic metabolic decompensation ": 34.54838936392488, "Diabetic neuropathy ": 9.022097189309632, "Diabetic retinal oedema ": 74.65499416522792, "Diabetic retinopathy ": 25.62535292506332, "Disability ": 4.110727697261855, "Drug dose omission by device ": 5.867757818378583, "Drug ineffective ": 2.0242300473953865, "Episcleritis ": 20.25263306984255, "Expired device used ": 22.927041270887827, "Expired product administered ": 14.903526541911017, "Exposure during pregnancy ": 3.5266191998398755, "Exposure via breast milk ": 4.679806767191686, "Extra dose administered ": 7.200250256029633, "Eye disorder ": 2.0224992256868477, "Eye haemorrhage ": 4.1376915037159385, "Feeding disorder ": 2.200481598379397, "Foetal death ": 2.6517066733453296, "Foetal exposure timing unspecified ": 31.996543563908563, "Foot fracture ": 2.231357501520031, "Glaucoma ": 2.369939819928134, "Glycosylated haemoglobin increased ": 18.337459709271396, "Haemodialysis ": 4.399460559223785, "Hospitalisation ": 2.695624824094257, "Hunger ": 10.082621613127468, "Hyperglycaemia ": 46.0319744874429, "Hyperhidrosis ": 2.609194761429089, "Hyperinsulinaemic hypoglycaemia ": 69.5945885267812, "Hyperphagia ": 6.448577327692834, "Hypoglycaemia ": 42.34131185817496, "Hypoglycaemia neonatal ": 6.384772064162495, "Hypoglycaemia unawareness ": 12.24910543048068, "Hypoglycaemic coma ": 26.75085237494848, "Hypoglycaemic encephalopathy ": 26.810776635127752, "Hypoglycaemic seizure ": 30.74112026948308, "Hypoglycaemic unconsciousness ": 36.21847582303528, "Incorrect dose administered ": 5.788217640698246, "Incorrect dose administered by device ": 18.20653141122177, "Induration ": 2.9074057633998875, "Infarction ": 2.5236176431260184, "Injection site abscess ": 5.370000190017354, "Injection site atrophy ": 10.28397994628966, "Injection site bruising ": 6.9708808808052725, "Injection site discolouration ": 15.114670136864794, "Injection site haematoma ": 2.073989742540092, "Injection site haemorrhage ": 9.32127309417551, "Injection site hypersensitivity ": 16.83129912904313, "Injection site induration ": 2.7167980293634484, "Injection site infection ": 5.354479576643265, "Injection site injury ": 12.294740008179598, "Injection site mass ": 2.4272433607256487, "Injection site nodule ": 7.265806005051203, "Injection site oedema ": 3.33371711902046, "Injection site urticaria ": 4.612655303432383, "Insulin resistance ": 9.37935011209292, "Intentional product misuse ": 2.351465915269948, "Intestinal haemorrhage ": 3.23129869500408, "Ketoacidosis ": 11.672285212230252, "Ketonuria ": 9.11514108200945, "Ketosis ": 10.538052985742596, "Kidney infection ": 2.0473225956662087, "Leg amputation ": 4.660726542374589, "Limb operation ": 5.10137353160867, "Lipoatrophy ": 7.125962489516124, "Lipodystrophy acquired ": 16.60002005215803, "Liquid product physical issue ": 7.7358756873391075, "Localised infection ": 3.8379834481655744, "Loss of consciousness ": 3.9167986581702574, "Macular degeneration ": 2.0058052895522818, "Macular oedema ": 8.016697006377177, "Maternal exposure timing unspecified ": 2.697791923505208, "Medication error ": 7.345847296120676, "Multiple lentigines syndrome ": 366.7779925124033, "Multiple use of single-use product ": 118.0375707069236, "Near death experience ": 3.485166423720468, "Nervousness ": 4.356519650079207, "Pancreatic carcinoma metastatic ": 2.781309411080744, "Pancreatic disorder ": 7.440167161696918, "Polydipsia ": 4.6502909501666005, "Poor quality product administered ": 4.811088468265711, "Postprandial hypoglycaemia ": 21.529138873615903, "Premature baby ": 2.436063399738545, "Product administration error ": 5.531902959028437, "Product complaint ": 8.971059113318463, "Product dispensing error ": 2.1700914004896266, "Product odour abnormal ": 4.190460787440595, "Product physical consistency issue ": 7.495901403956943, "Product prescribing error ": 2.753771634500222, "Product quality issue ": 7.321487308441586, "Product storage error ": 22.440878059765357, "Product use issue ": 3.203746619264044, "Reaction to excipient ": 3.455825536814637, "Renal disorder ": 2.498579569981992, "Renal transplant ": 4.630432785192785, "Retinal detachment ": 2.7577817439844647, "Retinal haemorrhage ": 3.028669202061544, "Retinopathy ": 8.404037389713883, "Road traffic accident ": 2.490099813857005, "Shock hypoglycaemic ": 20.10688559038641, "Sopor ": 16.184612484409396, "Substance use ": 12.853629370532426, "Tendon disorder ": 2.7638024226646825, "Therapeutic product effect delayed ": 6.61364248628943, "Therapeutic response decreased ": 2.578719328131786, "Thermal burn ": 4.782710996071542, "Thirst ": 3.5401881717143766, "Tinea infection ": 28.121610736862504, "Tinea pedis ": 16.430660482397638, "Toe amputation ": 7.771512294073851, "Type I hypersensitivity ": 3.5320080350561143, "Type III immune complex mediated reaction ": 47.4973388468732, "Type IV hypersensitivity reaction ": 2.6959263537112155, "Unevaluable event ": 2.7757365196115167, "Urine ketone body present ": 14.101791098860597, "Vision blurred ": 2.571685654584165, "Visual impairment ": 4.656397479508501, "Weight increased ": 3.0033977762618456, "Wheelchair user ": 6.771274412636358, "Wrong product administered ": 72.10811377078747, "Wrong technique in device usage process ": 7.34919612818718, "Wrong technique in product usage process ": 2.1722458020917} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/990.json new file mode 100644 index 00000000000..83c2b9e32ba --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/990.json @@ -0,0 +1 @@ +{"Acute kidney injury ": 3.534002050770199, "Angioedema ": 7.539282653142957, "Drug ineffective for unapproved indication ": 20.73629511858232, "Drug interaction ": 16.028467435603925, "Liver transplant rejection ": 340.61135450972023, "Off label use ": 3.729097752444501, "Product use in unapproved indication ": 8.569177872753905, "Transplant rejection ": 68.93462089310147} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/991.json new file mode 100644 index 00000000000..e90d93e216f --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/991.json @@ -0,0 +1 @@ +{"Alanine aminotransferase increased ": 4.805884049268032, "Anaemia ": 3.8919569772032, "Aspartate aminotransferase increased ": 4.228994240474632, "Blood potassium decreased ": 18.92882110415466, "Death ": 2.4279047452921247, "Drug-induced liver injury ": 11.673509466573538, "Electrocardiogram QT prolonged ": 112.0765038457217, "Haemoglobin decreased ": 2.7795116537951228, "Hepatic function abnormal ": 4.097208895425196, "Hypokalaemia ": 3.030467415493918, "Intentional product use issue ": 20.168822450481315, "Liver injury ": 12.052242875590746, "Neuropathy peripheral ": 7.838234172403804, "Off label use ": 5.954712686280971, "Product use issue ": 5.170778410045484, "Pulmonary tuberculosis ": 70.57367086101097, "Rash pruritic ": 3.546455720479756, "Respiratory failure ": 11.785268074799006} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/992.json new file mode 100644 index 00000000000..5556a4777ca --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/992.json @@ -0,0 +1 @@ +{"Acute kidney injury ": 2.587392476279438, "Angioedema ": 3.835539714065976, "Atrial fibrillation ": 3.154185122295811, "Blood glucose increased ": 2.143764055540013, "Completed suicide ": 19.66567288460777, "Diabetes mellitus ": 7.759073765927343, "Diabetes mellitus inadequate control ": 24.894974495762845, "Drug interaction ": 3.1260122672941804, "Hyperkalaemia ": 6.01427606706304, "Hypoglycaemia ": 13.790223559575583, "Infusion site extravasation ": 175.88972800076286, "Lactic acidosis ": 21.52830886033204, "Loss of consciousness ": 2.3883140827112337, "Pemphigoid ": 36.49822139696445, "Product monitoring error ": 290.8439585151044, "Toxicity to various agents ": 5.338830471858231, "Tremor ": 2.0420897356310355, "Wrong patient received product ": 94.19399297381086} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/993.json new file mode 100644 index 00000000000..d48ba8dbfd2 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/993.json @@ -0,0 +1 @@ +{"Completed suicide ": 102.5292937671624, "Intentional product misuse ": 101.95006512172726, "Toxicity to various agents ": 89.14388211807089} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/994.json new file mode 100644 index 00000000000..98425854fcf --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/994.json @@ -0,0 +1 @@ +{"Abortion spontaneous ": 2.6603026197685966, "Acne ": 2.9781726311055223, "Arthritis ": 2.6599646368819707, "Breast cancer ": 2.2396290525552947, "Breast cancer female ": 20.32500959336669, "C-reactive protein increased ": 2.1839893856036063, "Crohn's disease ": 4.50837570888682, "Dermatitis exfoliative generalised ": 7.194891813052414, "Device issue ": 13.560675352538166, "Eczema ": 4.736086608017973, "Fungal infection ": 4.248896072883334, "Hepatic cirrhosis ": 5.032679332844837, "Infection ": 2.076296230291741, "Injection site haemorrhage ": 7.501150440632723, "Intestinal obstruction ": 4.3577606665814885, "Lung neoplasm malignant ": 3.0857363616944395, "Lymphoma ": 9.202427564839976, "Maternal exposure during pregnancy ": 2.287321105344685, "Prostate cancer ": 4.411043624079024, "Psoriasis ": 52.788970015310994, "Psoriatic arthropathy ": 11.436602027411512, "Skin disorder ": 2.893564877162633, "Skin exfoliation ": 4.724383334782908, "Skin lesion ": 3.2214622849295544, "Skin plaque ": 19.38948657278382, "Stress ": 2.8421787837467627, "Surgery ": 3.857534673620018, "Therapeutic product effect decreased ": 3.301838321950351, "Therapeutic product effect incomplete ": 2.7402657450757384, "Therapeutic response shortened ": 65.13614588318256, "Tuberculosis ": 6.927601925234758, "Unevaluable event ": 14.657310260828504} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/995.json new file mode 100644 index 00000000000..ffcf99a6793 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/995.json @@ -0,0 +1 @@ +{"Aggression ": 75.87874501894635, "Agitation ": 33.4324342605909, "Irritability ": 30.747741661972785, "Middle insomnia ": 108.16237748116951, "Product administered to patient of inappropriate age ": 129.40971429495238, "Somnolence ": 3.3420522460603426} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/996.json new file mode 100644 index 00000000000..a5e3117581e --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/996.json @@ -0,0 +1 @@ +{"Ammonia increased ": 85.14768935177429, "Cardiac arrest ": 5.691845298571863, "Cerebrovascular insufficiency ": 1687.92266617122, "Cluster headache ": 93.0829645908044, "Coma ": 7.077070081568211, "Confusional state ": 4.934083684780522, "Drug abuse ": 8.448666755634182, "Drug interaction ": 14.412439204413706, "Drug level increased ": 21.253946300848245, "Electroencephalogram abnormal ": 87.68644476337025, "Eye movement disorder ": 46.17764180242136, "Inhibitory drug interaction ": 199.73286981245587, "Miosis ": 51.29912456556964, "Multiple organ dysfunction syndrome ": 10.636908014887943, "Myoclonus ": 24.15322610955697, "Overdose ": 17.66334240346588, "Somnolence ": 3.1921552910163924, "Toxicity to various agents ": 19.5116998130631} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/997.json new file mode 100644 index 00000000000..b7579aa727f --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/997.json @@ -0,0 +1 @@ +{"Anaemia ": 2.415525757893432, "Ascites ": 5.870984986841708, "Bradycardia ": 8.356652730122704, "Death ": 2.2323323476761026, "Drug ineffective ": 5.700443190181129, "Drug interaction ": 4.796295965875079, "Genotype drug resistance test positive ": 117.6370637123594, "Hepatitis C ": 72.37544742557667, "Hepatocellular carcinoma ": 23.772727215694548, "Intentional dose omission ": 99.27973837023455, "Product dose omission issue ": 6.241568586349409, "Treatment failure ": 27.035609476735512} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/998.json new file mode 100644 index 00000000000..30aefc3432f --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/998.json @@ -0,0 +1 @@ +{"Acute graft versus host disease ": 2.478358234942793, "Acute leukaemia ": 5.949533547804612, "Acute myeloid leukaemia ": 2.276415224685003, "Acute pulmonary oedema ": 2.366473995716444, "Adenovirus infection ": 3.1555051019269347, "Anaemia ": 2.565039342901669, "Antiphospholipid syndrome ": 6.005879457919846, "Anuria ": 5.166221789558011, "Aplastic anaemia ": 25.90175120911438, "Ascites ": 2.3419238942317158, "Aspergillus infection ": 3.883642484979247, "Atypical haemolytic uraemic syndrome ": 216.3983531703212, "Azotaemia ": 2.5321653911045474, "BK virus infection ": 6.9306087829626986, "Bacteraemia ": 11.145804522172426, "Bacterial infection ": 2.1304357343552662, "Bacterial sepsis ": 6.543925587176647, "Bilirubin conjugated increased ": 3.088625228958405, "Biopsy bone marrow ": 46.76781484618534, "Blood albumin decreased ": 3.505038087470169, "Blood alkaline phosphatase decreased ": 14.841952018907833, "Blood bilirubin abnormal ": 12.210732089417172, "Blood bilirubin increased ": 3.417550672733784, "Blood calcium decreased ": 3.1813955358978463, "Blood creatinine abnormal ": 15.802140752682744, "Blood creatinine decreased ": 5.051875513251869, "Blood creatinine increased ": 4.373496698708891, "Blood immunoglobulin G decreased ": 10.986152632239996, "Blood iron increased ": 10.427783985467917, "Blood lactate dehydrogenase abnormal ": 101.34597063900117, "Blood lactate dehydrogenase decreased ": 56.00349057592518, "Blood lactate dehydrogenase increased ": 35.60085408299439, "Blood phosphorus increased ": 3.863269243143953, "Blood product transfusion dependent ": 118.76351582461368, "Blood urea abnormal ": 11.157115973904633, "Blood urea increased ": 3.470609917540145, "Blood urine present ": 4.958396586578211, "Bone marrow disorder ": 3.3744199824965198, "Bone marrow failure ": 7.500506749184425, "Bone marrow transplant ": 23.455756218133427, "Brain death ": 4.301777384748771, "Brain herniation ": 3.4196445622305407, "Brain oedema ": 2.6145675610783314, "Breakthrough haemolysis ": 1446.759529463025, "Bronchopulmonary aspergillosis ": 2.0081406932870385, "Budd-Chiari syndrome ": 72.96835794595576, "C3 glomerulopathy ": 223.8140278735098, "Catheter site infection ": 9.41449924980452, "Catheter site pain ": 5.938609232789995, "Cellulitis ": 2.540578644706549, "Cerebral ischaemia ": 2.4499518259595185, "Cerebral thrombosis ": 2.8560551110615293, "Cholangitis ": 2.1464272869291823, "Cholecystitis ": 4.317567596492592, "Cholecystitis acute ": 2.0962157568382405, "Cholelithiasis ": 6.01150075147884, "Chromaturia ": 13.05094762921445, "Clostridium difficile colitis ": 2.129515562404018, "Clostridium difficile infection ": 3.514460961807502, "Complement factor C3 decreased ": 116.21100592287922, "Complement factor C4 decreased ": 40.69589737779844, "Complement factor abnormal ": 399.2111708483052, "Complement factor decreased ": 46.76781484618534, "Complement factor increased ": 93.0389962069208, "Complications of transplanted kidney ": 8.122790420817836, "Condition aggravated ": 3.835520609419027, "Congenital aplasia ": 3.287029783163081, "Coombs direct test positive ": 13.336696194738334, "Coombs test positive ": 36.323655983216646, "Critical illness ": 24.64823357335205, "Cytomegalovirus infection ": 2.962784070128101, "Cytomegalovirus viraemia ": 4.228851188833217, "Device related infection ": 18.38374204773497, "Device related sepsis ": 10.222546515519932, "Dialysis ": 9.089613092822114, "Disease complication ": 6.438250251137331, "Disease recurrence ": 4.0509259955231744, "Drug level below therapeutic ": 3.1295819537836214, "End stage renal disease ": 6.830664147567471, "Endocarditis ": 5.17153649138042, "Enterococcal infection ": 6.992351349020736, "Enterococcal sepsis ": 20.70417650545461, "Epstein-Barr viraemia ": 10.655160517689186, "Escherichia bacteraemia ": 7.350693579725144, "Escherichia infection ": 3.5555367976179983, "Escherichia sepsis ": 9.700010020606848, "Escherichia test positive ": 19.20546884435191, "Escherichia urinary tract infection ": 12.798199854839448, "Exposure during pregnancy ": 4.95084432075327, "Exposure via breast milk ": 2.737814209660672, "Extravascular haemolysis ": 1919.7828075689256, "Eyelid ptosis ": 2.8590461622136334, "Foetal death ": 2.0097005830904786, "Foetal distress syndrome ": 3.5202506094449846, "Foetal growth restriction ": 2.2726505064272544, "Gallbladder disorder ": 2.304502041323132, "Gastroenteritis ": 2.526082567188653, "Gastroenteritis viral ": 4.5738984238466704, "Gastrointestinal infection ": 3.210488869710817, "Gene mutation ": 18.92707525505111, "Glomerular filtration rate decreased ": 2.4117230144325097, "Glomerulonephritis ": 4.517016546393328, "Glomerulonephritis membranoproliferative ": 30.24916690227435, "Glomerulosclerosis ": 14.076968450905982, "Graft loss ": 50.3872008445028, "Graft versus host disease ": 9.755736146155233, "Graft versus host disease in gastrointestinal tract ": 3.332435899124008, "Haematocrit abnormal ": 22.55126218028763, "Haematocrit decreased ": 10.356739423965822, "Haematology test abnormal ": 36.99931267664951, "Haematuria ": 2.580322675520116, "Haemodialysis ": 5.917146356762338, "Haemoglobin abnormal ": 23.84354479832607, "Haemoglobin decreased ": 16.205545224929168, "Haemoglobinuria ": 371.4056217042755, "Haemolysis ": 192.81031087555183, "Haemolytic anaemia ": 5.002499370960031, "Haemolytic uraemic syndrome ": 58.054788372196384, "Haptoglobin abnormal ": 420.6650807916568, "Haptoglobin decreased ": 149.76344178660727, "Haptoglobin increased ": 96.85133304387536, "Hepatic vein thrombosis ": 30.239663279417364, "Hepatomegaly ": 2.0192498845453515, "Hospitalisation ": 7.735863960498301, "Hypervolaemia ": 7.358756562480629, "Immunosuppression ": 6.524575619371689, "Inappropriate schedule of product administration ": 6.142843112685863, "Incorrect dose administered ": 8.97936764452443, "Infection ": 4.402589324630535, "International normalised ratio decreased ": 2.1764887078622754, "Intestinal perforation ": 3.808176551217093, "Intravascular haemolysis ": 97.73568906188568, "Iron binding capacity total decreased ": 64.26689007438506, "Iron overload ": 32.60414501583814, "Jaundice ": 2.718728821578664, "Kidney fibrosis ": 11.370703177887169, "Kidney transplant rejection ": 14.985101057727126, "Klebsiella infection ": 7.068295718307272, "Laboratory test abnormal ": 13.700520684656396, "Low birth weight baby ": 2.0953899761895527, "Malignant hypertension ": 23.650686245210693, "Maternal exposure during breast feeding ": 2.504567731024204, "Mean cell volume increased ": 11.107163247770677, "Meningitis ": 6.487533766053176, "Meningitis meningococcal ": 111.5718939991666, "Meningococcal bacteraemia ": 207.8043086040115, "Meningococcal infection ": 242.7543101087164, "Meningococcal sepsis ": 335.3369801704848, "Microangiopathic haemolytic anaemia ": 10.146375979739236, "Microangiopathy ": 9.029373011729698, "Multimorbidity ": 34.63443148832581, "Multiple organ dysfunction syndrome ": 5.58569698589678, "Myasthenia gravis ": 43.35999711736493, "Myasthenia gravis crisis ": 157.05129187414656, "Myelodysplastic syndrome ": 9.82888400172119, "Necrotising fasciitis ": 3.525176853769997, "Neurological decompensation ": 6.687708171394188, "Neuromyelitis optica spectrum disorder ": 43.3034429151255, "Neutrophil count increased ": 2.2969193170329643, "Ocular icterus ": 3.6767950684675497, "Off label use ": 3.978882006778616, "Oliguria ": 2.401780381679244, "Pancytopenia ": 2.0656798948700525, "Paroxysmal nocturnal haemoglobinuria ": 341.02619745721444, "Pericardial effusion ": 2.042029565695339, "Peritonitis ": 3.420306724646078, "Peritonitis bacterial ": 7.502961139070839, "Plasmapheresis ": 44.02007672414733, "Platelet count abnormal ": 21.21316660301365, "Platelet count decreased ": 6.19643322816443, "Platelet count increased ": 3.206291831953534, "Platelet transfusion ": 10.450685731660364, "Pneumonia ": 2.137274505992892, "Pneumonia fungal ": 2.917763809911303, "Pneumonia klebsiella ": 8.790475350240348, "Poor venous access ": 47.56172966933303, "Portal hypertension ": 4.200131786818342, "Portal vein thrombosis ": 5.939272258552816, "Post procedural haemorrhage ": 4.40645166568044, "Posterior reversible encephalopathy syndrome ": 2.6519255309959227, "Postoperative wound infection ": 2.703345824660892, "Pre-eclampsia ": 7.7935883153693934, "Pregnancy ": 6.053885613760671, "Premature baby ": 2.6549410145049994, "Premature delivery ": 2.4634929034490574, "Procalcitonin increased ": 7.3629327914664335, "Protein urine present ": 2.159528002687648, "Proteinuria ": 6.018766268441128, "Pseudomonal sepsis ": 12.840627580830272, "Pseudomonas infection ": 6.825609567625249, "Pulmonary haemorrhage ": 6.182812603604899, "Pulmonary oedema ": 2.0590294775563405, "Pyelonephritis ": 2.1887411300806843, "Red blood cell count decreased ": 3.365340548700763, "Red blood cell schistocytes present ": 57.98788632389085, "Red blood cell transfusion ": 24.26143917712872, "Red cell distribution width increased ": 4.156781438887766, "Renal impairment ": 4.042232743342304, "Renal transplant ": 18.44691073834847, "Renal transplant failure ": 46.31826733669602, "Renal tubular necrosis ": 2.4225284528929056, "Respiratory failure ": 2.4692892217199107, "Respiratory tract infection ": 4.528831017994116, "Respiratory tract infection viral ": 6.825116666609919, "Reticulocyte count increased ": 112.93651513627036, "Reticulocytosis ": 45.13466966658407, "SARS-CoV-2 test positive ": 4.838366183420367, "Scleroderma ": 4.50555135793533, "Sepsis ": 5.153488382121923, "Septic shock ": 6.13758482147272, "Serum ferritin increased ": 9.984120278895205, "Splenomegaly ": 3.8200350769207656, "Staphylococcal bacteraemia ": 5.9768115884475455, "Staphylococcal infection ": 4.152381685386734, "Staphylococcal sepsis ": 10.176987260901477, "Suspected COVID-19 ": 8.466035033613304, "Symptom recurrence ": 8.449623123579581, "Terminal state ": 2.657530068205909, "Therapeutic response shortened ": 4.101116030953178, "Thrombosis ": 2.2037143568700666, "Thrombotic microangiopathy ": 55.79067919032297, "Thrombotic thrombocytopenic purpura ": 3.3535379076915657, "Total complement activity decreased ": 1002.0522991421444, "Total complement activity increased ": 1159.028160661451, "Transfusion ": 16.60125081570065, "Transfusion reaction ": 20.802075077006705, "Transplant dysfunction ": 9.890275038463871, "Transplant failure ": 16.061658812125795, "Transplant rejection ": 24.032326702736743, "Treatment noncompliance ": 2.0433348947919527, "Unevaluable event ": 3.083328262944219, "Upper respiratory tract infection ": 4.291966417716509, "Urinary tract infection ": 3.318577053368496, "Urine output decreased ": 2.367064845381979, "Urosepsis ": 2.560234902103685, "Uterine leiomyoma ": 2.7909059933957154, "Vascular device infection ": 6.553491076826704, "Viral infection ": 8.17613756144806, "Viral upper respiratory tract infection ": 6.560302115070571, "White blood cell count abnormal ": 2.6088109657321885} \ No newline at end of file diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/999.json new file mode 100644 index 00000000000..d991cf77681 --- /dev/null +++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/999.json @@ -0,0 +1 @@ +{"Abscess limb ": 27.31409671249371, "Acne ": 3.2689167459726987, "Apnoea ": 12.316305373243914, "Autoimmune thyroiditis ": 14.285540665721554, "Blood alkaline phosphatase increased ": 3.775187826782616, "Blood follicle stimulating hormone increased ": 128.62945455890866, "Brain neoplasm ": 32.95469153570535, "Cerebral infarction ": 3.2111979663106425, "Condition aggravated ": 2.159508749101408, "Contusion ": 3.217902387412193, "Craniopharyngioma ": 626.4802843396005, "Dehydration ": 3.0906426770053077, "Diabetes mellitus ": 5.843430255987122, "Disease recurrence ": 10.460935280923849, "Drug abuse ": 4.682739818575517, "Drug-induced liver injury ": 10.747992718368042, "Eating disorder ": 4.873289348430135, "Electrolyte imbalance ": 9.670530122271732, "Enteritis ": 18.699391002719537, "Epiphysiolysis ": 722.4450930132522, "Fluid retention ": 3.469666284043281, "Focal nodular hyperplasia ": 148.3289695208738, "Focal segmental glomerulosclerosis ": 77.75742512517103, "Gastrointestinal infection ": 38.17183352978912, "Glucose tolerance impaired ": 68.31341766630216, "Glycosylated haemoglobin increased ": 3.522666981774041, "Head injury ": 4.360510550601289, "Hepatic cirrhosis ": 26.67277078647569, "Hepatic encephalopathy ": 44.40357586596575, "Hepatic necrosis ": 118.82859525466692, "Hepatomegaly ": 11.912783809452428, "Hepatotoxicity ": 13.493550296518764, "Hypoglycaemia ": 2.576678649672792, "Hyponatraemic seizure ": 386.1438015596223, "Hypophagia ": 6.471100344467632, "Idiopathic intracranial hypertension ": 241.6653602346964, "Increased appetite ": 10.64671010133172, "Injection site atrophy ": 88.83987535467666, "Injection site bruising ": 10.547298936069764, "Injection site haemorrhage ": 9.86754881187074, "Insulin resistance ": 35.62490278094377, "Insulin-like growth factor increased ": 278.57056558083264, "Intentional product misuse ": 2.0170800566277776, "Intracranial pressure increased ": 58.61924593764471, "Lower limb fracture ": 9.307119250187409, "Meningioma ": 56.60556288884906, "Myocardial fibrosis ": 99.93713553370924, "Neoplasm recurrence ": 93.530186464796, "Obstructive sleep apnoea syndrome ": 93.44473712164935, "Oesophageal disorder ": 49.96482074252936, "Off label use ": 3.064367880555756, "Pancreatitis acute ": 6.354695258301056, "Panniculitis ": 25.471415284247072, "Papilloedema ": 23.66846701604428, "Pituitary tumour benign ": 63.016160763225535, "Pleural adhesion ": 349.2422085660759, "Product dose omission issue ": 2.4982479017417747, "Product prescribing error ": 10.437622371213305, "Protein-losing gastroenteropathy ": 185.394968085309, "Scoliosis ": 87.56623486100816, "Sleep apnoea syndrome ": 37.15198603838651, "Snoring ": 88.88864192627597, "Stress ": 2.4625437485970263, "Sudden death ": 18.379653723577015, "Sulphaemoglobinaemia ": 1290.8221809123604, "Therapeutic response unexpected ": 3.0383413805651585, "Tonsillar disorder ": 271.355272624483, "Type 1 diabetes mellitus ": 7.415810809777687, "Type 2 diabetes mellitus ": 6.847951891042719, "Viral infection ": 4.7167327495039295} \ No newline at end of file